Consensus Paper: Cerebellar Development

Ketty Leto*, Marife Arancillo, Esther B E Becker, Annalisa Buffo, Chin Chiang, Baojin Ding, William B. Dobyns, Isabelle Dusart, Parthiv Haldipur, Mary E. Hatten, Mikio Hoshino, Alexandra L. Joyner, Masanobu Kano, Daniel L. Kilpatrick, Noriyuki Koibuchi, Silvia Marino, Salvador Martinez, Kathleen J. Millen, Thomas O. Millner, Takaki MiyataElena Parmigiani, Karl Schilling, Gabriella Sekerková, Roy V. Sillitoe, Constantino Sotelo, Naofumi Uesaka, Annika Wefers, Richard J T Wingate, Richard Hawkes

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

282 Citations (Scopus)

Abstract

The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and inductive environmental influences. Here, we describe the main processes of cerebellar ontogenesis, highlighting the neurogenic strategies used by developing progenitors, the genetic programs involved in cell fate specification, the progressive changes of structural organization, and some of the better-known abnormalities associated with developmental disorders of the cerebellum.

Original languageEnglish
JournalCerebellum (London, England)
DOIs
Publication statusAccepted/In press - 6 Oct 2015

Keywords

  • Cerebellum
  • Differentiation
  • Progenitors
  • Purkinje cells
  • Specification

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