@article{bf1968538598492a861fd039fdecf3e3,
title = "Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research",
abstract = "We read with interest the multiomic studies by Kong et al and Chen et al examining gut microbiome-metabolome interactions and potential diagnostic and classification biomarkers in colorectal cancer.1 2 Large-scale, multicentre, multisample, longitudinal studies are imperative to understand complex relationships between the metabolome and digestive diseases.",
keywords = "BILE ACID METABOLISM, GLUCOSE METABOLISM, LIPID METABOLISM",
author = "Alexander, {James L.} and Wyatt, {Nicola J.} and Stephane Camuzeaux and Elena Chekmeneva and Beatriz Jimenez and Sands, {Caroline J.} and Hannah Fuller and Panteleimon Takis and Tariq Ahmad and Doyle, {Jennifer A.} and Ailsa Hart and Irving, {Peter M.} and Kennedy, {Nicholas A.} and Lees, {Charlie W.} and Lindsay, {James O.} and McIntyre, {Rebecca E.} and Miles Parkes and Prescott, {Natalie J.} and Tim Raine and Jack Satsangi and Speight, {Richard Alexander} and Luke Jostins-Dean and Nick Powell and Marchesi, {Julian R.} and Stewart, {Christopher J.} and Lamb, {Christopher A.}",
note = "Funding Information: This work is supported by a research grant from The Leona M. and Harry B. Helmsley Charitable Trust (grant #2002-04255). IBD-RESPONSE is supported by the Medical Research Council (grant MR/T032162/1). We are grateful for support from the Newcastle Clinical Trials Unit, the National Phenome Centre, Imperial College London and the NIHR Biomedical Research Centres from Newcastle, Imperial and Cambridge. JLA is the recipient of an NIHR Academic Clinical Lectureship (CL-2019-21-502), funded by Imperial College London and The Joyce and Norman Freed Charitable Trust. NJW is an Academic Clinical Fellow supported by the NIHR. LJD is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 208750/Z/17/Z) and the Kennedy Trust for Rheumatology Research. CJS is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 221745/Z/20/Z) and the 2021 Lister Institute Prize Fellow Award. The views expressed are those of the authors and not necessarily those of our funders, the NIHR or the Department of Health and Social Care. Figure 1A was created with BioRender.com. Funding Information: This study involves human participants. Human samples used in this research project were obtained from the Imperial College Healthcare Tissue Bank (ICHTB). ICHTB is supported by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Imperial College Healthcare NHS Trust and Imperial College London. ICHTB is approved by Wales REC3 to release human material for research (17/WA/0161). Participants gave informed consent to participate in the study before taking part.",
year = "2023",
month = feb,
day = "8",
doi = "10.1136/gutjnl-2022-329297",
language = "English",
volume = "73",
pages = "379--383",
journal = "Gut",
issn = "0017-5749",
publisher = "BMJ Publishing Group",
number = "2",
}