Contemporary management of acute and chronic deep venous thrombosis

Prakash Saha, Stephen Black, Karen Breen, Ashish Patel, Bijan Modarai*, Alberto Smith

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

21 Citations (Scopus)


Introduction This review aims to provide an update on the management of deep vein thrombosis (DVT). Sources of data A systematic search of PubMed, Google Scholar and Cochrane databases was carried out. Areas of agreement Direct oral anticoagulants (DOACs) are as effective and easier to use than vitamin K antagonists for the treatment of DVT. Catheter-directed thrombolysis can reduce post thrombotic syndrome in patients with iliofemoral DVT. Compression bandaging can help heal a venous ulcer. Areas of controversy Compression hosiery to prevent post thrombotic syndrome. Long-Term evidence to show clinical benefit of using endovenous therapies to restore deep vein patency. Growing points Developing imaging methods to identify patients who would benefit from venous thrombolysis. The evolution of dedicated venous stents. Areas timely for developing research Understanding the mechanisms that lead to stent occlusion and investigation into the appropriate treatments that could prevent in-stent thrombosis is required.

Original languageEnglish
Pages (from-to)107-120
Number of pages14
JournalBritish Medical Bulletin
Issue number1
Publication statusPublished - 1 Mar 2016


  • catheter-directed lysis
  • DVT
  • endovenous
  • post-Thrombotic syndrome
  • thrombolysis
  • venous stent


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