Contrast-enhanced specific absorption rate-efficient 3D cardiac cine with respiratory-triggered radiofrequency gating

Markus Henningsson*, Raymond H. Chan, Beth Goddu, Lois A. Goepfert, Reza Razavi, Rene M. Botnar, Tobias Schaeffter, Reza Nezafat

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Purpose: To investigate the use of radiofrequency (RF) gating in conjunction with a paramagnetic contrast agent to reduce the specific absorption rate (SAR) and increase the blood-myocardium contrast in balanced steady-state free precession (bSSFP) 3D cardiac cine. Materials and Methods: RF gating was implemented by synchronizing the RF-excitation with an external respiratory sensor (bellows), which could additionally be used for respiratory gating. For reference, respiratory-gated 3D cine images were acquired without RF gating. Free-breathing 3D cine images were acquired in eight healthy subjects before and after contrast injection (Gd-BOPTA) and compared to breath-hold 2D cine. Results: RF-gated 3D cine reduced the SAR by nearly 40% without introducing significant artifacts while providing left ventricle (LV) measurements similar to those obtained with 2D cine. The contrast-to-noise ratio (CNR) was significantly higher for 3D cine compared to 2D cine, both before and after contrast injection; however, no statistically significant CNR increase was observed for the postcontrast 3D cine compared to the precontrast acquisitions. Conclusion: Respiratory-triggered RF gating significantly reduces SAR in 3D cine acquisitions, which may enable a more widespread clinical use of 3D cine. Furthermore, CNR of 3D bSSFP cine is higher than of 2D and administration of Gd-BOPTA does not improve the CNR of 3D cine. J. Magn. Reson. Imaging 2013;37:986992. (c) 2012 Wiley Periodicals, Inc.

Original languageEnglish
Pages (from-to)986-992
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Volume37
Issue number4
DOIs
Publication statusPublished - Apr 2013

Keywords

  • CARDIOVASCULAR MAGNETIC-RESONANCE
  • LEFT-VENTRICULAR FUNCTION
  • QUANTIFICATION
  • HEART-FAILURE
  • contrast enhanced
  • AGENT
  • 3D cine
  • SAR
  • SINGLE BREATH-HOLD
  • VOLUMES
  • CORONARY MR-ANGIOGRAPHY
  • ECHOCARDIOGRAPHY
  • INTERSTUDY REPRODUCIBILITY
  • RF gating

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