Copy number variation at chromosome 5q21.2 is associated with intraocular pressure

TY - JOUR

T1 - Copy number variation at chromosome 5q21.2 is associated with intraocular pressure

AU - Nag, Abhishek

AU - Venturini, Cristina

AU - Hysi, Pirro G

AU - Arno, Matthew

AU - Aldecoa-Otalora Astarloa, Estibaliz

AU - Macgregor, Stuart

AU - Hewitt, Alex W

AU - Young, Terri L

AU - Mitchell, Paul

AU - Viswanathan, Ananth C

AU - Mackey, David A

AU - Hammond, Christopher J

PY - 2013

Y1 - 2013

N2 - Glaucoma is a major cause of blindness in the world. Recent genome-wide association studies (GWAS) have identified common genetic variants for glaucoma, but still a significant heritability gap remains. We hypothesized that copy number variants (CNVs) might influence part of the susceptibility to glaucoma or its related quantitative endophenotypes.

AB - Glaucoma is a major cause of blindness in the world. Recent genome-wide association studies (GWAS) have identified common genetic variants for glaucoma, but still a significant heritability gap remains. We hypothesized that copy number variants (CNVs) might influence part of the susceptibility to glaucoma or its related quantitative endophenotypes.

U2 - 10.1167/iovs.13-11952

DO - 10.1167/iovs.13-11952

M3 - Article

C2 - 23599335

SN - 1552-5783

VL - 54

SP - 3607

EP - 3612

JO - Investigative Ophthalmology & Visual Science

JF - Investigative Ophthalmology & Visual Science

IS - 5

ER -