Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study

Tevfik F. Ismail; Li-Yueh Hsu; Anders M. Greve; Carla Gonçalves; Andrew Jabbour; Ankur Gulati; Benjamin Hewins; Niraj Mistry; Ricardo Wage; Michael Roughton; Pedro F. Ferreira; Peter Gatehouse; David Firmin; Rory O'Hanlon; Dudley J. Pennell; Sanjay K. Prasad; Andrew E. Arai

doi:10.1186/s12968-014-0049-1

Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study

Tevfik F. Ismail, Li-Yueh Hsu, Anders M. Greve, Carla Gonçalves, Andrew Jabbour, Ankur Gulati, Benjamin Hewins, Niraj Mistry, Ricardo Wage, Michael Roughton, Pedro F. Ferreira, Peter Gatehouse, David Firmin, Rory O'Hanlon, Dudley J. Pennell, Sanjay K. Prasad, Andrew E. Arai

Imaging and Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Abstract

Microvascular dysfunction in HCM has been associated with adverse clinical outcomes. Advances in quantitative cardiovascular magnetic resonance (CMR) perfusion imaging now allow myocardial blood flow to be quantified at the pixel level. We applied these techniques to investigate the spectrum of microvascular dysfunction in hypertrophic cardiomyopathy (HCM) and to explore its relationship with fibrosis and wall thickness.

Original language	Undefined/Unknown
Pages (from-to)	49
Number of pages	1
Journal	Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Volume	16
Issue number	1
DOIs	https://doi.org/10.1186/s12968-014-0049-1
Publication status	Published - 12 Aug 2014

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https://doi.org/10.1186/s12968-014-0049-1

Cite this

Ismail, T. F., Hsu, L.-Y., Greve, A. M., Gonçalves, C., Jabbour, A., Gulati, A., Hewins, B., Mistry, N., Wage, R., Roughton, M., Ferreira, P. F., Gatehouse, P., Firmin, D., O'Hanlon, R., Pennell, D. J., Prasad, S. K., & Arai, A. E. (2014). Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 16(1), 49. https://doi.org/10.1186/s12968-014-0049-1

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abstract = "Microvascular dysfunction in HCM has been associated with adverse clinical outcomes. Advances in quantitative cardiovascular magnetic resonance (CMR) perfusion imaging now allow myocardial blood flow to be quantified at the pixel level. We applied these techniques to investigate the spectrum of microvascular dysfunction in hypertrophic cardiomyopathy (HCM) and to explore its relationship with fibrosis and wall thickness.",

author = "Ismail, {Tevfik F.} and Li-Yueh Hsu and Greve, {Anders M.} and Carla Gon{\c c}alves and Andrew Jabbour and Ankur Gulati and Benjamin Hewins and Niraj Mistry and Ricardo Wage and Michael Roughton and Ferreira, {Pedro F.} and Peter Gatehouse and David Firmin and Rory O'Hanlon and Pennell, {Dudley J.} and Prasad, {Sanjay K.} and Arai, {Andrew E.}",

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Ismail, TF, Hsu, L-Y, Greve, AM, Gonçalves, C, Jabbour, A, Gulati, A, Hewins, B, Mistry, N, Wage, R, Roughton, M, Ferreira, PF, Gatehouse, P, Firmin, D, O'Hanlon, R, Pennell, DJ, Prasad, SK & Arai, AE 2014, 'Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study', Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, vol. 16, no. 1, pp. 49. https://doi.org/10.1186/s12968-014-0049-1

Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study. / Ismail, Tevfik F.; Hsu, Li-Yueh; Greve, Anders M. et al.
In: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Vol. 16, No. 1, 12.08.2014, p. 49.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study

AU - Ismail, Tevfik F.

AU - Hsu, Li-Yueh

AU - Greve, Anders M.

AU - Gonçalves, Carla

AU - Jabbour, Andrew

AU - Gulati, Ankur

AU - Hewins, Benjamin

AU - Mistry, Niraj

AU - Wage, Ricardo

AU - Roughton, Michael

AU - Ferreira, Pedro F.

AU - Gatehouse, Peter

AU - Firmin, David

AU - O'Hanlon, Rory

AU - Pennell, Dudley J.

AU - Prasad, Sanjay K.

AU - Arai, Andrew E.

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Y1 - 2014/8/12

N2 - Microvascular dysfunction in HCM has been associated with adverse clinical outcomes. Advances in quantitative cardiovascular magnetic resonance (CMR) perfusion imaging now allow myocardial blood flow to be quantified at the pixel level. We applied these techniques to investigate the spectrum of microvascular dysfunction in hypertrophic cardiomyopathy (HCM) and to explore its relationship with fibrosis and wall thickness.

AB - Microvascular dysfunction in HCM has been associated with adverse clinical outcomes. Advances in quantitative cardiovascular magnetic resonance (CMR) perfusion imaging now allow myocardial blood flow to be quantified at the pixel level. We applied these techniques to investigate the spectrum of microvascular dysfunction in hypertrophic cardiomyopathy (HCM) and to explore its relationship with fibrosis and wall thickness.

U2 - 10.1186/s12968-014-0049-1

DO - 10.1186/s12968-014-0049-1

M3 - Article

SN - 1532-429X

VL - 16

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JO - Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

JF - Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

IS - 1

ER -

Ismail TF, Hsu LY, Greve AM, Gonçalves C, Jabbour A, Gulati A et al. Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 2014 Aug 12;16(1):49. doi: 10.1186/s12968-014-0049-1