Objectives: The objective of the analysis is to understand whether the AVATAR 6 psychological therapy is cost-effective, as it has already been shown to be clinically effective.
Perspective: The perspective taken is the health and social services perspective. Setting: South London and the Maudsley NHS Foundation Trust in South London, England, United Kingdom.
Methods (study design and inputs): The trial was a single-blind randomised control trial, the first powered randomised trial of AVATAR therapy. 150 eligible patients were randomly assigned to AVATAR therapy or supportive counselling.
Results (base case and uncertainty analysis): The increase in quality adjusted life years measured using the EQ-5D-5L was slightly higher for AVATAR therapy than for supportive counselling (mean difference 0.018, bootstrapped standard deviation = 0.011)
Conclusions: AVATAR therapy has been found to the dominant strategy provides clear benefit over the control treatment) in terms of cost-effectiveness using the QALY measure using the five-level questionnaire. Costs are shown to reduce slightly and outcomes to improve slightly.