Cutaneous Manifestations of ESRD

Timur A. Galperin; Antonia J. Cronin; Kieron S. Leslie

doi:10.2215/CJN.05900513

Cutaneous Manifestations of ESRD

Timur A. Galperin^*, Antonia J. Cronin, Kieron S. Leslie

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

A broad range of skin diseases occurs in patients with ESRD: from the benign and asymptomatic to the physically disabling and life-threatening. Many of them negatively impact on quality of life. Their early recognition and treatment are essential in reducing morbidity and mortality. The cutaneous manifestations can be divided into two main categories: nonspecific and specific. The nonspecific manifestations are commonly seen and include skin color changes, xerosis, half-and-half nails, and pruritus. The specific disorders include acquired perforating dermatosis, bullous dermatoses, metastatic calcification, and nephrogenic systemic fibrosis. This review article describes these conditions and considers the underlying pathophysiology, clinical presentations, diagnosis, and treatment options.

Original language	English
Pages (from-to)	201-218
Number of pages	18
Journal	Journal of the American Society of Nephrology
Volume	9
Issue number	1
DOIs	https://doi.org/10.2215/CJN.05900513
Publication status	Published - 7 Jan 2014

Keywords

NEPHROGENIC SYSTEMIC FIBROSIS
ACQUIRED PERFORATING DERMATOSIS
STAGE RENAL-DISEASE
CALCIFIC UREMIC ARTERIOLOPATHY
BAND ULTRAVIOLET-B
OF-THE-LITERATURE
IMATINIB MESYLATE TREATMENT
RANDOMIZED CONTROLLED-TRIAL
CHRONIC KIDNEY-DISEASE
DOUBLE-BLIND TRIAL

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title = "Cutaneous Manifestations of ESRD",

abstract = "A broad range of skin diseases occurs in patients with ESRD: from the benign and asymptomatic to the physically disabling and life-threatening. Many of them negatively impact on quality of life. Their early recognition and treatment are essential in reducing morbidity and mortality. The cutaneous manifestations can be divided into two main categories: nonspecific and specific. The nonspecific manifestations are commonly seen and include skin color changes, xerosis, half-and-half nails, and pruritus. The specific disorders include acquired perforating dermatosis, bullous dermatoses, metastatic calcification, and nephrogenic systemic fibrosis. This review article describes these conditions and considers the underlying pathophysiology, clinical presentations, diagnosis, and treatment options.",

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author = "Galperin, {Timur A.} and Cronin, {Antonia J.} and Leslie, {Kieron S.}",

year = "2014",

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journal = "Journal of the American Society of Nephrology",

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AU - Galperin, Timur A.

AU - Cronin, Antonia J.

AU - Leslie, Kieron S.

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N2 - A broad range of skin diseases occurs in patients with ESRD: from the benign and asymptomatic to the physically disabling and life-threatening. Many of them negatively impact on quality of life. Their early recognition and treatment are essential in reducing morbidity and mortality. The cutaneous manifestations can be divided into two main categories: nonspecific and specific. The nonspecific manifestations are commonly seen and include skin color changes, xerosis, half-and-half nails, and pruritus. The specific disorders include acquired perforating dermatosis, bullous dermatoses, metastatic calcification, and nephrogenic systemic fibrosis. This review article describes these conditions and considers the underlying pathophysiology, clinical presentations, diagnosis, and treatment options.

AB - A broad range of skin diseases occurs in patients with ESRD: from the benign and asymptomatic to the physically disabling and life-threatening. Many of them negatively impact on quality of life. Their early recognition and treatment are essential in reducing morbidity and mortality. The cutaneous manifestations can be divided into two main categories: nonspecific and specific. The nonspecific manifestations are commonly seen and include skin color changes, xerosis, half-and-half nails, and pruritus. The specific disorders include acquired perforating dermatosis, bullous dermatoses, metastatic calcification, and nephrogenic systemic fibrosis. This review article describes these conditions and considers the underlying pathophysiology, clinical presentations, diagnosis, and treatment options.

KW - NEPHROGENIC SYSTEMIC FIBROSIS

KW - ACQUIRED PERFORATING DERMATOSIS

KW - STAGE RENAL-DISEASE

KW - CALCIFIC UREMIC ARTERIOLOPATHY

KW - BAND ULTRAVIOLET-B

KW - OF-THE-LITERATURE

KW - IMATINIB MESYLATE TREATMENT

KW - RANDOMIZED CONTROLLED-TRIAL

KW - CHRONIC KIDNEY-DISEASE

KW - DOUBLE-BLIND TRIAL

U2 - 10.2215/CJN.05900513

DO - 10.2215/CJN.05900513

M3 - Article

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JO - Journal of the American Society of Nephrology

JF - Journal of the American Society of Nephrology

IS - 1

ER -

Cutaneous Manifestations of ESRD

Abstract

Keywords

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