Cyclic peptides as ADAM protease inhibitors

TY - PAT

T1 - Cyclic peptides as ADAM protease inhibitors

AU - Koller, Garrit Peter

AU - Bartsch, Joerg Walter

PY - 2017/1/17

Y1 - 2017/1/17

N2 - The invention relates to a method for inhibiting an ADAM protease, comprising inhibiting binding to an integrin-binding loop of a disintegrin domain in the ADAM protease. Also provided are cyclic peptides which inhibit binding to an integrin-binding loop of an ADAM protease, as well as associated pharmaceutical compositions, uses and methods of treatment.Type: Grant

AB - The invention relates to a method for inhibiting an ADAM protease, comprising inhibiting binding to an integrin-binding loop of a disintegrin domain in the ADAM protease. Also provided are cyclic peptides which inhibit binding to an integrin-binding loop of an ADAM protease, as well as associated pharmaceutical compositions, uses and methods of treatment.Type: Grant

M3 - Patent

M1 - 9546198

ER -