Dentine remineralization induced by two bioactive glasses developed for air abrasion purposes

Zhejun Wang, Tao Jiang, Salvatore Sauro, Yining Wang, Ian Thompson, Timothy F Watson, Yue Sa, Wenzhong Xing, Ya Shen, Markus Haapasalo

Research output: Contribution to journalArticlepeer-review

69 Citations (Scopus)

Abstract

Objectives
The present study aimed to evaluate dentine remineralization through a 7-day period of artificial saliva (AS) storage induced by bioactive glass 45S5 (BAG) and by bioactive glass modified with soda-lime spherical glass.

Methods
Partially demineralized dentine disks were treated by BAG or the spherical-glass modified bioactive glass (M-BAG) and subsequently immersed in AS for 7 days. Attenuated Total Reflection Fourier Transform Infrared Spectroscopy (ATR-FTIR) was used to quantitatively analyse the mineral variation of the dentine surface by calculating the spectra parameters. X-ray diffraction (XRD) and energy-dispersive X-ray analysis (EDX) were performed on completely demineralized dentine to confirm the apatite formation. The roughness of the dentine surface was evaluated by atomic force microscopy (AFM) and the morphology was also examined by scanning electron microscopy (SEM).

Results
ATR-FTIR showed a significant increase of the mineral matrix area ratio in dentine specimens treated with the two bioactive glasses subsequent to 7 days of AS storage. The XRD spectrum exhibited apatite growth and mineral elements could be found on completely demineralized samples analysed by EDX after remineralization treatments. The dentine specimens treated with bioactive glass showed lower roughness, and most of the dentinal tubules appeared completely occluded during the AFM and SEM examination.

Conclusions
Although the concentration of bioactive glass in the M-BAG is 60% of that contained in the original version, both formulations have similar potential in dentine remineralization. These bioactive powders developed for air-abrasive use may be considered as innovative bioactive materials for therapeutic remineralization of dental hard tissues.
Original languageEnglish
Pages (from-to)746-756
Number of pages11
JournalJournal of Dentistry
Volume39
Issue number11
DOIs
Publication statusPublished - Nov 2011

Fingerprint

Dive into the research topics of 'Dentine remineralization induced by two bioactive glasses developed for air abrasion purposes'. Together they form a unique fingerprint.

Cite this