Abstract
Depression is characterized by an over activity of the hypothalamic-pituitary-adrenal (HPA) axis that resembles the neuroendocrine response to stress. These HPA axis abnormalities participate in the development of depressive symptoms. Moreover, antidepressants directly regulate HPA axis function. These novel findings are reshaping our understanding of the causes and treatment of this disabling disorder.
Original language | English |
---|---|
Pages (from-to) | 811 - 812 |
Number of pages | 2 |
Journal | Journal of Neuroendocrinology |
Volume | 15 |
Issue number | 8 |
Publication status | Published - 1 Aug 2003 |