Detection of ventricular enlargement in patients at the earliest clinical stage of MS

TY - JOUR

T1 - Detection of ventricular enlargement in patients at the earliest clinical stage of MS

AU - Brex, P A

AU - Jenkins, R

AU - Fox, N C

AU - Crum, W R

AU - O'Riordan, J I

AU - Plant, G T

AU - Miller, D H

PY - 2000/4/25

Y1 - 2000/4/25

N2 - The aim of this study was to determine whether atrophy could be detected at the earliest clinical stages of MS. Patients were selected from a 1-year follow-up MRI study of clinically isolated syndromes. Nine patients who developed MS were compared with eight matched patients who had no further symptoms. Significant ventricular enlargement occurred in the group that developed MS but not in the other group. Our findings show that atrophy, albeit mild, can be detected early in the course of MS.

AB - The aim of this study was to determine whether atrophy could be detected at the earliest clinical stages of MS. Patients were selected from a 1-year follow-up MRI study of clinically isolated syndromes. Nine patients who developed MS were compared with eight matched patients who had no further symptoms. Significant ventricular enlargement occurred in the group that developed MS but not in the other group. Our findings show that atrophy, albeit mild, can be detected early in the course of MS.

U2 - 10.1212/WNL.54.8.1689

DO - 10.1212/WNL.54.8.1689

M3 - Article

SN - 0028-3878

VL - 54

SP - 1689

EP - 1691

JO - Neurology

JF - Neurology

IS - 8

ER -