Determination of successful Reperfusion after thrombolysis for acute myocardial infarction - A noninvasive method using ultrasonic tissue characterization that can be applied clinically

TY - JOUR

T1 - Determination of successful Reperfusion after thrombolysis for acute myocardial infarction - A noninvasive method using ultrasonic tissue characterization that can be applied clinically

AU - Hancock, J E

AU - Cooke, J C

AU - Chin, D T

AU - Monaghan, M J

PY - 2002/1/15

Y1 - 2002/1/15

N2 - Background-The aim of the present study was to determine the use of cyclic variation in ultrasonic integrated backscatter (IBS), which is reduced in ischemic myocardium, to predict an occluded infarct-related artery (IRA) after thrombolysis for acute myocardial infarction (AMI). This is important, because patency of the IRA 90 minutes after thrombolysis has been shown to predict outcome. Methods and Results-One hundred thirteen patients with AMI had peak-to-peak cyclic IBS measured in the myocardial territory supplied by their IRA as well as a remote territory with normal function from the parasternal long- or short-axis view. This analysis took 5 to 10 minutes. Wall motion score index was assessed, and coronary angiography, to determine patency of the IRA, was performed in all patients. Cyclic IBS in the IRA territory was much lower in segments supplied by an occluded IRA (3.3 versus 4.6 dB, P

AB - Background-The aim of the present study was to determine the use of cyclic variation in ultrasonic integrated backscatter (IBS), which is reduced in ischemic myocardium, to predict an occluded infarct-related artery (IRA) after thrombolysis for acute myocardial infarction (AMI). This is important, because patency of the IRA 90 minutes after thrombolysis has been shown to predict outcome. Methods and Results-One hundred thirteen patients with AMI had peak-to-peak cyclic IBS measured in the myocardial territory supplied by their IRA as well as a remote territory with normal function from the parasternal long- or short-axis view. This analysis took 5 to 10 minutes. Wall motion score index was assessed, and coronary angiography, to determine patency of the IRA, was performed in all patients. Cyclic IBS in the IRA territory was much lower in segments supplied by an occluded IRA (3.3 versus 4.6 dB, P

UR - http://www.scopus.com/inward/record.url?scp=0037080905&partnerID=8YFLogxK

U2 - 10.1161/hc0202.102116

DO - 10.1161/hc0202.102116

M3 - Article

SN - 1524-4539

VL - 105

SP - 157

EP - 161

JO - Circulation (Baltimore)

JF - Circulation (Baltimore)

IS - 2

ER -