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Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry

Research output: Contribution to journal › Article › peer-review

Andy Man Chung Lau, Zainab Ahdash, Chloe Martens, Argyris Politis

Original languageEnglish
JournalBIOINFORMATICS
Accepted/In press29 Dec 2018

Documents

  • LAU_Bioinformatics_Deuteros

    Deuteros_revision_manuscript_bioinformatics_cc.pdf, 1.2 MB, application/pdf

    Uploaded date:09 Jan 2019

    Version:Accepted author manuscript

    Licence:CC BY

King's Authors

Abstract

Hydrogen deuterium exchange-mass spectrometry (HDX-MS) has emerged as a powerful technique for interrogating the conformational dynamics of proteins and their complexes. Currently, analysis of HDX-MS data remains a laborious procedure, mainly due to the lack of streamlined software to process the large datasets. We present Deuteros which is a standalone software designed to be coupled with Waters DynamX HDX data analysis software, allowing the rapid analysis and visualization of data from differential HDX-MS.

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