Development of antidrug antibodies against adalimumab maps to variation within the HLA-DR peptide-binding groove

Biomarkers of Systemic Treatment Outcomes in Psoriasis (BSTOP) Study Group, Teresa Tsakok, Jake Saklatvala, Theo Rispens, Floris C Loeff, Annick de Vries, Michael H Allen, Ines A Barbosa, David Baudry, Tejus Dasandi, Michael Duckworth, Freya Meynell, Alice Russell, Anna Chapman, Sandy McBride, Kevin McKenna, Gayathri Perera, Helen Ramsay, Raakhee Ramesh, Kathleen SandsAlexa Shipman, A David Burden, Christopher Em Griffiths, Nick J Reynolds, Richard B Warren, Satveer Mahil, Jonathan Barker, Nick Dand, Catherine Smith, Michael A. Simpson

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Immunology and Microbiology