Development of the Addiction Dimensions for Assessment and Personalised Treatment (ADAPT)

John Marsden*, Brian Eastwood, Robert Ali, Pete Burkinshaw, Gagandeep Chohan, Alex Copello, Daniel Burn, Michael Kelleher, Luke Mitcheson, Steve Taylor, Nick Wilson, Chris Whiteley, Edward Day

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

Background: Convergent research reveals heterogeneity in substance use disorders (SUD). The Addiction Dimensions for Assessment and Personalised Treatment (ADAPT) is designed to help clinicians tailor therapies.

Methods: Multicentre study in 21 SUD clinics in London, Birmingham (England) and Adelaide (Australia). 132 clinicians rated their caseload on a beta version with 16 ordinal indicators of addiction severity, health and social problem complexity, and recovery strengths constructs. In Birmingham, two in-treatment outcomes were recorded after 15-months: 28-day drug use (Treatment Outcome Profile; n = 703) and Global Assessment of Functioning (GAF; DSM-IV Axis V; n = 695). Following item-level screening (inter-rater reliability [IRR]; n = 388), exploratory structural equation models (ESEM), latent profile analysis (LPA), and mixed-effects regression evaluated construct, concurrent and predictive validity characteristics, respectively.

Results: 2467 patients rated (majority opioid or stimulant dependent, enrolled in opioid medication assisted or psychological treatment). IRR-screening removed two items and ESEM models identified and recalibrated remaining indicators (root mean square error of approximation 0.066 [90% confidence interval 0.055-0.064]). Following minor re-specification and satisfactory measurement invariance evaluation, ADAPT factor scores discriminated patients by sample, addiction therapy and drug use. LPA identified three patient sub-types: Class 1 (moderate severity, moderate complexity, high strengths profile; 46.9%); Class 2(low severity, low complexity, high strengths; 25.4%) and Class 3 (high severity, high complexity, low strengths; 27.7%). Class 2 had higher GAF (z = 4.30). Class 3 predicted follow-up drug use (z = 2.02) and lower GAF (z = 3.51).

Conclusion: The ADAPT is a valid instrument for SUD treatment planning, clinical review and outcome evaluation. Scoring and application are discussed.

Original languageEnglish
Pages (from-to)121-131
Number of pages11
JournalDrug and alcohol dependence
Volume139
DOIs
Publication statusPublished - 1 Jun 2014

Keywords

  • ADAPT
  • Substance use disorder
  • Treatment
  • Assessment
  • Personalised
  • SUBSTANCE-USE DISORDERS
  • TREATMENT OUTCOMES
  • SEVERITY INDEX
  • MODEL
  • SCALE
  • INVOLVEMENT
  • PERFORMANCE
  • SERVICES
  • SMOKING
  • HEROIN

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