Development of the mammalian main olfactory bulb

Candida Tufo; Subathra Poopalasundaram; Ana Dorrego-Rivas; Marc C. Ford; Anthony Graham; Matthew S. Grubb

doi:10.1242/dev.200210

Development of the mammalian main olfactory bulb

Candida Tufo, Subathra Poopalasundaram, Ana Dorrego-Rivas, Marc C. Ford, Anthony Graham, Matthew S. Grubb^*

^*Corresponding author for this work

Developmental Neurobiology

King's College London

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

The mammalian main olfactory bulb is a crucial processing centre for the sense of smell. The olfactory bulb forms early during development and is functional from birth. However, the olfactory system continues to mature and change throughout life as a target of constitutive adult neurogenesis. Our Review synthesises current knowledge of prenatal, postnatal and adult olfactory bulb development, focusing on the maturation, morphology, functions and interactions of its diverse constituent glutamatergic and GABAergic cell types.We highlight not only the great advances in the understanding of olfactory bulb development made in recent years, but also the gaps in our present knowledge that most urgently require addressing.

Original language	English
Article number	dev200210
Journal	Development (Cambridge)
Volume	149
Issue number	3
Early online date	11 Feb 2022
DOIs	https://doi.org/10.1242/dev.200210
Publication status	Published - Feb 2022

Keywords

Adult neurogenesis
Maturation
Olfaction
Olfactory bulb development

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10.1242/dev.200210

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abstract = "The mammalian main olfactory bulb is a crucial processing centre for the sense of smell. The olfactory bulb forms early during development and is functional from birth. However, the olfactory system continues to mature and change throughout life as a target of constitutive adult neurogenesis. Our Review synthesises current knowledge of prenatal, postnatal and adult olfactory bulb development, focusing on the maturation, morphology, functions and interactions of its diverse constituent glutamatergic and GABAergic cell types.We highlight not only the great advances in the understanding of olfactory bulb development made in recent years, but also the gaps in our present knowledge that most urgently require addressing. ",

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AU - Graham, Anthony

AU - Grubb, Matthew S.

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Development of the mammalian main olfactory bulb

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Keywords

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