TY - JOUR
T1 - Devices for Episodic Migraine
T2 - Past, Present, and Future
AU - Moreno-Ajona, David
AU - Hoffmann, Jan
AU - Akerman, Simon
N1 - Funding Information:
Simon Akerman is supported by a National Institute of Neurological Disorders and Stroke (NINDS) grant, NS120930.
Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2022/3
Y1 - 2022/3
N2 - Purpose of Review: Historically, therapies for migraine have generally involved pharmacological treatments using non-selective or selective analgesics and preventive treatments. However, for many patients these treatments are not effective, while others prefer to use non-pharmacological-based therapies. To fill this need, over the last 15 years, neuromodulatory devices have entered the market for migraine treatment. Here, we will review the most recent findings for the use of these devices in the treatment of migraine. Recent Findings: Non-invasive vagus nerve stimulation and spring-pulse transcranial magnetic stimulation are both cleared for the treatment of migraine, supported by preclinical studies that validate efficacy and mechanism of action, and complemented with clinical trial data. Other options also authorized for use include transcutaneous supraorbital nerve stimulation and remote electrical neuromodulation. Summary: Various options are available to treat migraine using authorized neuromodulatory devices. These data support their efficacy in the treatment of episodic migraine, although further studies are necessary to elucidate their mechanism of action and to provide rigor to clinical trial data.
AB - Purpose of Review: Historically, therapies for migraine have generally involved pharmacological treatments using non-selective or selective analgesics and preventive treatments. However, for many patients these treatments are not effective, while others prefer to use non-pharmacological-based therapies. To fill this need, over the last 15 years, neuromodulatory devices have entered the market for migraine treatment. Here, we will review the most recent findings for the use of these devices in the treatment of migraine. Recent Findings: Non-invasive vagus nerve stimulation and spring-pulse transcranial magnetic stimulation are both cleared for the treatment of migraine, supported by preclinical studies that validate efficacy and mechanism of action, and complemented with clinical trial data. Other options also authorized for use include transcutaneous supraorbital nerve stimulation and remote electrical neuromodulation. Summary: Various options are available to treat migraine using authorized neuromodulatory devices. These data support their efficacy in the treatment of episodic migraine, although further studies are necessary to elucidate their mechanism of action and to provide rigor to clinical trial data.
UR - http://www.scopus.com/inward/record.url?scp=85124622856&partnerID=8YFLogxK
U2 - 10.1007/s11916-022-01024-y
DO - 10.1007/s11916-022-01024-y
M3 - Review article
C2 - 35147856
AN - SCOPUS:85124622856
SN - 1531-3433
VL - 26
SP - 259
EP - 265
JO - Current pain and headache reports
JF - Current pain and headache reports
IS - 3
ER -