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Differences in Frontal Network Anatomy Across Primate Species

Research output: Contribution to journalArticle

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Differences in Frontal Network Anatomy Across Primate Species. / Barrett, Rachel L C; Dawson, Matthew; Dyrby, Tim B; Krug, Kristine; Ptito, Maurice; D'Arceuil, Helen; Croxson, Paula L; Johnson, Philippa J; Howells, Henrietta; Forkel, Stephanie J; Dell'Acqua, Flavio; Catani, Marco.

In: Journal of Neuroscience, Vol. 40, No. 10, 04.03.2020, p. 2094-2107.

Research output: Contribution to journalArticle

Harvard

Barrett, RLC, Dawson, M, Dyrby, TB, Krug, K, Ptito, M, D'Arceuil, H, Croxson, PL, Johnson, PJ, Howells, H, Forkel, SJ, Dell'Acqua, F & Catani, M 2020, 'Differences in Frontal Network Anatomy Across Primate Species', Journal of Neuroscience, vol. 40, no. 10, pp. 2094-2107. https://doi.org/10.1523/JNEUROSCI.1650-18.2019

APA

Barrett, R. L. C., Dawson, M., Dyrby, T. B., Krug, K., Ptito, M., D'Arceuil, H., ... Catani, M. (2020). Differences in Frontal Network Anatomy Across Primate Species. Journal of Neuroscience, 40(10), 2094-2107. https://doi.org/10.1523/JNEUROSCI.1650-18.2019

Vancouver

Barrett RLC, Dawson M, Dyrby TB, Krug K, Ptito M, D'Arceuil H et al. Differences in Frontal Network Anatomy Across Primate Species. Journal of Neuroscience. 2020 Mar 4;40(10):2094-2107. https://doi.org/10.1523/JNEUROSCI.1650-18.2019

Author

Barrett, Rachel L C ; Dawson, Matthew ; Dyrby, Tim B ; Krug, Kristine ; Ptito, Maurice ; D'Arceuil, Helen ; Croxson, Paula L ; Johnson, Philippa J ; Howells, Henrietta ; Forkel, Stephanie J ; Dell'Acqua, Flavio ; Catani, Marco. / Differences in Frontal Network Anatomy Across Primate Species. In: Journal of Neuroscience. 2020 ; Vol. 40, No. 10. pp. 2094-2107.

Bibtex Download

@article{ff71254413874361a74fad8b9e222ae0,
title = "Differences in Frontal Network Anatomy Across Primate Species",
abstract = "The frontal lobe is central to distinctive aspects of human cognition and behavior. Some comparative studies link this to a larger frontal cortex and even larger frontal white matter in humans compared with other primates, yet others dispute these findings. The discrepancies between studies could be explained by limitations of the methods used to quantify volume differences across species, especially when applied to white matter connections. In this study, we used a novel tractography approach to demonstrate that frontal lobe networks, extending within and beyond the frontal lobes, occupy 66{\%} of total brain white matter in humans and 48{\%} in three monkey species: vervets (Chlorocebus aethiops), rhesus macaque (Macaca mulatta) and cynomolgus macaque (Macaca fascicularis), all male. The simian- human differences in proportional frontal tract volume were significant for projection, commissural, and both intralobar and interlobar association tracts. Among the long association tracts, the greatest difference was found for tracts involved in motor planning, auditory memory, top-down control of sensory information, and visuospatial attention, with no significant differences in frontal limbic tracts important for emotional processing and social behaviour. In addition, we found that a nonfrontal tract, the anterior commissure, had a smaller volume fraction in humans, suggesting that the disproportionally large volume of human frontal lobe connections is accompanied by a reduction in the proportion of some nonfrontal connections. These findings support a hypothesis of an overall rearrangement of brain connections during human evolution.",
keywords = "Comparative anatomy, Connectivity, Diffusion MRI, Evolution, Frontal lobe, Tractography",
author = "Barrett, {Rachel L C} and Matthew Dawson and Dyrby, {Tim B} and Kristine Krug and Maurice Ptito and Helen D'Arceuil and Croxson, {Paula L} and Johnson, {Philippa J} and Henrietta Howells and Forkel, {Stephanie J} and Flavio Dell'Acqua and Marco Catani",
note = "Copyright {\circledC} 2020 Barrett et al.",
year = "2020",
month = "3",
day = "4",
doi = "10.1523/JNEUROSCI.1650-18.2019",
language = "English",
volume = "40",
pages = "2094--2107",
journal = "Journal of Neuroscience",
issn = "0270-6474",
number = "10",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Differences in Frontal Network Anatomy Across Primate Species

AU - Barrett, Rachel L C

AU - Dawson, Matthew

AU - Dyrby, Tim B

AU - Krug, Kristine

AU - Ptito, Maurice

AU - D'Arceuil, Helen

AU - Croxson, Paula L

AU - Johnson, Philippa J

AU - Howells, Henrietta

AU - Forkel, Stephanie J

AU - Dell'Acqua, Flavio

AU - Catani, Marco

N1 - Copyright © 2020 Barrett et al.

PY - 2020/3/4

Y1 - 2020/3/4

N2 - The frontal lobe is central to distinctive aspects of human cognition and behavior. Some comparative studies link this to a larger frontal cortex and even larger frontal white matter in humans compared with other primates, yet others dispute these findings. The discrepancies between studies could be explained by limitations of the methods used to quantify volume differences across species, especially when applied to white matter connections. In this study, we used a novel tractography approach to demonstrate that frontal lobe networks, extending within and beyond the frontal lobes, occupy 66% of total brain white matter in humans and 48% in three monkey species: vervets (Chlorocebus aethiops), rhesus macaque (Macaca mulatta) and cynomolgus macaque (Macaca fascicularis), all male. The simian- human differences in proportional frontal tract volume were significant for projection, commissural, and both intralobar and interlobar association tracts. Among the long association tracts, the greatest difference was found for tracts involved in motor planning, auditory memory, top-down control of sensory information, and visuospatial attention, with no significant differences in frontal limbic tracts important for emotional processing and social behaviour. In addition, we found that a nonfrontal tract, the anterior commissure, had a smaller volume fraction in humans, suggesting that the disproportionally large volume of human frontal lobe connections is accompanied by a reduction in the proportion of some nonfrontal connections. These findings support a hypothesis of an overall rearrangement of brain connections during human evolution.

AB - The frontal lobe is central to distinctive aspects of human cognition and behavior. Some comparative studies link this to a larger frontal cortex and even larger frontal white matter in humans compared with other primates, yet others dispute these findings. The discrepancies between studies could be explained by limitations of the methods used to quantify volume differences across species, especially when applied to white matter connections. In this study, we used a novel tractography approach to demonstrate that frontal lobe networks, extending within and beyond the frontal lobes, occupy 66% of total brain white matter in humans and 48% in three monkey species: vervets (Chlorocebus aethiops), rhesus macaque (Macaca mulatta) and cynomolgus macaque (Macaca fascicularis), all male. The simian- human differences in proportional frontal tract volume were significant for projection, commissural, and both intralobar and interlobar association tracts. Among the long association tracts, the greatest difference was found for tracts involved in motor planning, auditory memory, top-down control of sensory information, and visuospatial attention, with no significant differences in frontal limbic tracts important for emotional processing and social behaviour. In addition, we found that a nonfrontal tract, the anterior commissure, had a smaller volume fraction in humans, suggesting that the disproportionally large volume of human frontal lobe connections is accompanied by a reduction in the proportion of some nonfrontal connections. These findings support a hypothesis of an overall rearrangement of brain connections during human evolution.

KW - Comparative anatomy

KW - Connectivity

KW - Diffusion MRI

KW - Evolution

KW - Frontal lobe

KW - Tractography

UR - http://www.scopus.com/inward/record.url?scp=85081080277&partnerID=8YFLogxK

U2 - 10.1523/JNEUROSCI.1650-18.2019

DO - 10.1523/JNEUROSCI.1650-18.2019

M3 - Article

C2 - 31949106

VL - 40

SP - 2094

EP - 2107

JO - Journal of Neuroscience

JF - Journal of Neuroscience

SN - 0270-6474

IS - 10

ER -

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