DIFFUSE OPTICAL IMAGING OF THE NEWBORN INFANT BRAIN

Jeremy C. Hebden*, Marta Varela, Salavat Magazov, Nick Everdell, Adam Gibson, Judith Meek, Topun Austin, Marta Varela

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference paper

10 Citations (Scopus)

Abstract

Diffuse optical imaging has been developed at University College London (UCL) as a new method of assessing cerebral function and pathology in the newborn infant brain. The technique exploits the relative transparency of biological tissue to near-infrared light (700-1000nm) and the wavelength dependent absorption characteristics of hemoglobin, which vary with oxygenation. Methods have been developed to localize rapid hemodynamic changes resulting from functional activation of the cerebral cortex, and to generate three-dimensional images representing the spatial variation in cerebral blood volume and oxygenation. Previous studies have also been made of the brains of infants with intraventricular hemorrhage, hypoxic-ischemic injury, and epileptic seizures. This paper summarizes preliminary measurements performed with a new time-resolved system.

Original languageEnglish
Title of host publication2012 9TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI)
PublisherIEEE
Pages503-505
Number of pages3
ISBN (Print)978-1-4577-1858-8
Publication statusPublished - 2012
Event9th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro - Barcelona, Spain
Duration: 2 May 20125 May 2012

Conference

Conference9th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro
Country/TerritorySpain
Period2/05/20125/05/2012

Keywords

  • Diffuse optical imaging
  • medical imaging
  • optical tomography
  • infant brain imaging
  • TOMOGRAPHY

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