Diffusion tensor MRI of the corpus callosum and cognitive function in adults born preterm

TY - JOUR

T1 - Diffusion tensor MRI of the corpus callosum and cognitive function in adults born preterm

AU - Kontis, Dimitris

AU - Catani, Marco

AU - Cuddy, Marion

AU - Walshe, Muriel

AU - Nosarti, Chiara

AU - Jones, Derek

AU - Wyatt, John

AU - Rifkin, Larry

AU - Murray, Robin

AU - Allin, Matthew

PY - 2009/3/4

Y1 - 2009/3/4

N2 - Very preterm birth (before 33 weeks gestation) is associated with the white matter damage, and a common sequel is reduced size and altered shape of the corpus callosum. We used diffusion tensor MRI to assess the corpus callosum in 63 very preterm and 45 term-born young adults. Indices of white matter microstructure [fractional anisotropy (FA) and mean diffusivity (MD)] were obtained for the genu, body and splenium. Very preterm females had higher MD in the genu than term-born females, indicating altered white matter microstructure. This was associated with lower performance la The groups demonstrated different patterns of correlations between verbal learning and tract-specific FA and MD, consistent with the reorganization of white matter structure in adults born very preterm. NeuroReport 20:424-428 (C) 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.

AB - Very preterm birth (before 33 weeks gestation) is associated with the white matter damage, and a common sequel is reduced size and altered shape of the corpus callosum. We used diffusion tensor MRI to assess the corpus callosum in 63 very preterm and 45 term-born young adults. Indices of white matter microstructure [fractional anisotropy (FA) and mean diffusivity (MD)] were obtained for the genu, body and splenium. Very preterm females had higher MD in the genu than term-born females, indicating altered white matter microstructure. This was associated with lower performance la The groups demonstrated different patterns of correlations between verbal learning and tract-specific FA and MD, consistent with the reorganization of white matter structure in adults born very preterm. NeuroReport 20:424-428 (C) 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.

U2 - 10.1097/WNR.0b013e328325a8f9

DO - 10.1097/WNR.0b013e328325a8f9

M3 - Article

VL - 20

SP - 424

EP - 428

JO - Neuroreport

JF - Neuroreport

IS - 4

ER -