King's College London

Research portal

Digital Signal Processing for Molecular Communication via Chemical-Reaction-Based Microfluidic Circuits

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number9446679
Pages (from-to)26-32
Number of pages7
Issue number5
PublishedMay 2021

Bibliographical note

Funding Information: AcknowledGMent This work was funded by the EPSRC, U.K., under Grant EP/T000937/1. Publisher Copyright: © 1979-2012 IEEE. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

King's Authors


Chemical-reaction-based microfluidic circuits are expected to provide new opportunities to perform signal processing functions over the molecular domain. To realize this vision, in this article, we exploit and present the digital signal processing capabilities of chemical-reaction-based microfluid-ic circuits. To facilitate microfluidic circuit design, we describe a microfluidic circuit using a five-level architecture: molecular propagation, chemical transformation, microfluidic modules, microfluidic logic gates, and microfluidic circuits. We first identify the components at Levels 1 and 2, and present how their combinations can build the basic modules for Level 3. We then assemble basic modules to construct five types of logic gates for Level 4, including AND, NAND, OR, NOR, and XOR gates, which show advantages of microfluidic circuits in versatility and modularity. Finally, we discuss challenges and potential solutions for designing, building, and testing microfluidic circuits with complex signal processing functions in Level 5 based on the digital logic gates at Level 4.

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454