King's College London

Research portal

Distortion correction in fetal EPI using non-rigid registration with Laplacian constraint

Research output: Chapter in Book/Report/Conference proceedingConference paper

Maria Murgasova, Georgia Lockwood estrin , Mary Ann Rutherford, Daniel Rueckert, Joseph Vilmos Hajnal

Original languageEnglish
Title of host publication2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)
PublisherIEEE Computer Society Press
Number of pages4
ISBN (Print)9781479923502
Publication statusE-pub ahead of print - 16 Jun 2016
Event2016 IEEE 13th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 - Prague, Czech Republic
Duration: 13 Apr 201616 Apr 2016


Conference2016 IEEE 13th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016
CountryCzech Republic


King's Authors


We present a novel method for correction of geometric distortions induced by main B0 field in fetal EPI. The method estimates distortion by making the EPI data consistent with reconstructed T2 weighted ssFSE volume. The algorithm consists of two interleaved registration processes: rigid registration of EPI slices with T2 volume to correct for motion; and deformable registration with Laplacian constraint to correct for geometric distortion of EPI slices in a manner consistent with a source free background B0 field. Our results show that the Laplacian constraint significantly improves estimation of the distortion field and EPI volume reconstructed using the proposed method achieves better consistency with T2 weighted volume than EPI volume reconstructed from data corrected by B0 field map.

Download statistics

No data available

View graph of relations

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454