Distributed Beamforming for Localization of Brain Seizure Sources from Intracranial EEG Array

Sepehr Shirani, Bahman Abdi-Sargezeh, Antonio Valentin, Gonzalo Alarcon, Delaram Jarchi, Jordan Bird, Saeid Sanei

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The main objective here is to accurately localize delayed responses (DRs) to deep brain stimulation. The DRs are expected to originate from the interictal epileptiform discharge (IED) sources. Therefore, before the localization of DRs, we exploit the similarity between consecutive IEDs in designing a robust distributed localization system to identify the epileptogenic brain zone more accurately. The proposed beamformer exploits the morphology of IED and DR signals as a constraint in its formulation. The beamformer is then applied to a cortical EEG electrode array (a.k.a mat). It is demonstrated that it is highly likely for an epileptic subject that the IEDs and DRs originate from the same location in the brain. Therefore, to identify the seizure source, it is possible to localize well-controlled DRs instead of relying on IEDs, which may not be frequent.

Original languageEnglish
Pages (from-to)1117-1121
Number of pages5
JournalEuropean Signal Processing Conference
DOIs
Publication statusPublished - 2024
Event32nd European Signal Processing Conference, EUSIPCO 2024 - Lyon, France
Duration: 26 Aug 202430 Aug 2024

Keywords

  • Delayed responses
  • Distributed bemformer
  • EEG
  • Epilepsy
  • IEDs
  • Seizure
  • SPES

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