Dithiocarbamate complexes as radiopharmaceuticals for medical imaging

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41 Citations (Scopus)

Abstract

Over the past 30 years dithiocarbamate ligands have found application in radiopharmaceutical metal-ligand complexes to image a range of disease states. The vast majority of research and applications, and the widest range of complex structures, have involved radionuclides of technetium and rhenium. Considering the extent of coordination chemistry of dithiocarbamate ligands described elsewhere in this issue, the extent of radiopharmaceutical application with metallic radionuclides is surprisingly narrow. Here we summarise the types of radiopharmaceutical complexes studied and the uses, and potential uses, to which they have been put in nuclear medicine.

Original languageEnglish
Pages (from-to)1174-1183
Number of pages10
JournalMINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume12
Issue number12
DOIs
Publication statusPublished - Oct 2012

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