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Diverging from Nature: A New Reactivity for Molecular Synthesizers

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)2862-2864
Number of pages3
JournalChem
Volume6
Issue number11
DOIs
Published5 Nov 2020

Bibliographical note

Publisher Copyright: © 2020 Elsevier Inc. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

King's Authors

Abstract

Previous generations of artificial molecular synthesizers, inspired by the ribosome, have depended on amide-bond formation to generate sequence-specific oligomers. Dr. Charlie McTernan discusses how, with Dr. Guillaume De Bo and Prof. David Leigh, he designed and synthesized a carbon–carbon bond-forming molecular machine. This molecular assembler moves along a track while iteratively joining together building blocks to form an oligomer of single sequence with a continuous backbone of carbon–carbon bonds.

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