TY - JOUR
T1 - Diversity and inclusion in behavioural intervention trials in multiple sclerosis: A commentary
AU - Sidhu, Nimreth
AU - Proudfoot, Hannah
AU - Adan, Hiba
AU - Fawson, Sophie
AU - Moss-Morris, Rona
PY - 2024/7/30
Y1 - 2024/7/30
N2 - There is growing evidence that characteristics such as ethnicity, sex, gender, age, comorbidity, ability and social determinants of health (SDoH) are associated with poorer health outcomes for people living with MS (pwMS).1-3 Despite having the greatest needs, people from minoritised groups are underrepresented in MS research.1 Following a recent international workshop, Marrie and colleagues1 developed recommendations to improve the diversity and inclusion (D&I) of clinical trials for MS (see Table 1). Their recommendations were largely based on the shortcomings of clinical trials of drug modifying therapies (DMTs). In this commentary, we expand on Marrie and colleagues’1 D&I recommendations in relation to developing and trialling complex behavioural MS interventions, and present some of the challenges in this area. To do this, we draw on the work of REFUEL-MS, a research programme co-funded by the National Institute for Health and Care Research (NIHR) and MS Society, which aims to develop, test, and implement a digital behavioural intervention to reduce MS fatigue.
AB - There is growing evidence that characteristics such as ethnicity, sex, gender, age, comorbidity, ability and social determinants of health (SDoH) are associated with poorer health outcomes for people living with MS (pwMS).1-3 Despite having the greatest needs, people from minoritised groups are underrepresented in MS research.1 Following a recent international workshop, Marrie and colleagues1 developed recommendations to improve the diversity and inclusion (D&I) of clinical trials for MS (see Table 1). Their recommendations were largely based on the shortcomings of clinical trials of drug modifying therapies (DMTs). In this commentary, we expand on Marrie and colleagues’1 D&I recommendations in relation to developing and trialling complex behavioural MS interventions, and present some of the challenges in this area. To do this, we draw on the work of REFUEL-MS, a research programme co-funded by the National Institute for Health and Care Research (NIHR) and MS Society, which aims to develop, test, and implement a digital behavioural intervention to reduce MS fatigue.
KW - Multiple Sclerosis
KW - Health Inequities
KW - Fatigue
KW - diversity
KW - social determinants of health
UR - http://www.scopus.com/inward/record.url?scp=85199991107&partnerID=8YFLogxK
U2 - 10.1177/13524585241248279
DO - 10.1177/13524585241248279
M3 - Review article
VL - 30
SP - 927
EP - 933
JO - Multiple Sclerosis Journal
JF - Multiple Sclerosis Journal
IS - 8
ER -