Do salivary proteins play a role in tasting bitter substances?

Guy H. Carpenter*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The detection of bitterness occurs via well characterized receptors located in taste buds on the tongue surface. However, genetic variations in these receptors do not account for all the variations between subjects in their perception of bitter substances, which suggests there may be a role for salivary proteins or other factors in their detection. Several groups have shown associations of bitterness perception with carbonic anhydrase 6, proline-rich proteins and cystatins either by GWAS studies or proteomic studies, suggesting they potentially play a role. Some preliminary data is shown by the authors which provides further evidence that salivary proteins may play a role but the responsible protein is not determined, which may reflect the multifunctionality of salivary proteins.

Original languageEnglish
Title of host publicationACS Symposium Series
PublisherAmerican Chemical Society
Pages183-195
Number of pages13
Volume1191
ISBN (Print)9780841230699
DOIs
Publication statusPublished - 15 Jun 2015

Publication series

NameACS Symposium Series
Volume1191
ISSN (Print)00976156
ISSN (Electronic)19475918

Fingerprint

Dive into the research topics of 'Do salivary proteins play a role in tasting bitter substances?'. Together they form a unique fingerprint.

Cite this