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Does fetal fibronectin testing change patient management in women at risk of preterm labour?

Research output: Contribution to journalArticle

Lauren A. Bolt, Manju Chandiramani, Annemarie De Greeff, Paul Seed, Andrew H. Shennan

Original languageEnglish
Pages (from-to)180 - 183
Number of pages4
JournalEuropean Journal of Obstetrics Gynecology and Reproductive Biology
Issue number2
Publication statusPublished - Oct 2009

King's Authors


Objective: To determine clinicians' indications for, and actions following, fetal fibronectin testing in both symptomatic and asymptomatic women between 23(+0) and 34(+6) weeks' gestation. Study design: Following clinician education of the predictive ability of fetal fibronectin testing, results of all fetal fibronectin tests done at St Thomas' Hospital over a 6-week period were analysed. Clinicians were asked if the result changed management and if a reciprocal result would have altered management. Results: Ninety-seven fetal fibronectin tests were conducted of which 21 (22%) were positive. Follow-up was done for 91 tests of which 25 (28%) test results directly changed management; 81 (89%) test results had the potential to change management independent of the test result. Conclusion: The results of fetal fibronectin testing directly influenced management in a significant number of patients. A large number of women were asymptomatic at testing. Fetal fibronectin testing could be offered more widely and has the potential to benefit patient management. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

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