Abstract
In most Western countries there is a widespread belief, fostered in part by historical prejudice and religious proscription, that inbreeding in human populations causes a reduction in fertility. Support for this belief has been claimed in HLA-based studies, with increased rates of fetal losses suggested in HLA-compatible unions. To critically assess the overall status of fertility in consanguineous unions, data on 30 populations resident in six countries were collated from a systematic review of the literature. The mean numbers of live births were then compared in four consanguinity test categories, ranging from second cousin to uncle-niece/double first cousin, and corresponding non-consanguineous reference groups. Linear regressions indicated a positive association between consanguinity and fertility at all levels of inbreeding, attaining statistical significance at first cousin level (p
| Original language | English |
|---|---|
| Pages (from-to) | 111-130 |
| Number of pages | 20 |
| Journal | Annals of Human Biology |
| Volume | 29 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2002 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- RECURRENT SPONTANEOUS-ABORTIONS
- CONSANGUINEOUS MARRIAGE
- PARENTAL CONSANGUINITY
- ANDHRA-PRADESH
- SOUTH-INDIA
- REPRODUCTIVE COMPENSATION
- CHILDHOOD MORTALITY
- MUSLIM POPULATION
- MATE SELECTION
- HLA
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