Does Post-Withdrawal Cue Exposure Improve Outcome In Opiate Addiction?: A Controlled Trial

Sharon Dawe; Jane Powell; David Richards; Michael  Gossop; Isaac Marks; John Strang; Jeffrey A GRAY

doi:10.1111/j.1360-0443.1993.tb02146.x

Does Post-Withdrawal Cue Exposure Improve Outcome In Opiate Addiction? A Controlled Trial

Sharon Dawe, Jane Powell, David Richards, Michael Gossop, Isaac Marks, John Strang, Jeffrey A GRAY

Research output: Contribution to journal › Article › peer-review

82 Citations (Scopus)

Abstract

A controlled trial studied whether cue exposure prevented relapse in opiate addiction. Subjects were randomly allocated to one of two inpatient treatment settings: a drug dependence unit with a special 10 week program and 4 weeks in a behavioural/general treatment unit without such a program. In each setting, following drug-withdrawal, subjects had either cue exposure for at least six sessions over 3 weeks, or a control condition. Subjects were followed up twice, at about 6 weeks and 6 months post-treatment. 186 subjects were randomly allocated; 69 were assessed post-detoxification, and of these 43 completed cue exposure or control treatments. Cue exposure and control subjects did not differ in cue reactivity. This was evaluated post-treatment for cue exposure subjects and at a comparable time point for controls. All groups showed a significant decrement in cue-elicited craving, withdrawal responses and negative mood. Cue exposure and control subjects did not differ at either of the two follow up interviews.

Original language	English
Article number	N/A
Pages (from-to)	1233-1245
Number of pages	13
Journal	Addiction
Volume	88
Issue number	9
DOIs	https://doi.org/10.1111/j.1360-0443.1993.tb02146.x
Publication status	Published - Sept 1993

Keywords

SMOKING CESSATION
SELF-EFFICACY
MANAGEMENT
ALCOHOLICS
DRINKING
RELAPSE
ABUSE

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/j.1360-0443.1993.tb02146.x

Cite this

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title = "Does Post-Withdrawal Cue Exposure Improve Outcome In Opiate Addiction?: A Controlled Trial",

abstract = "A controlled trial studied whether cue exposure prevented relapse in opiate addiction. Subjects were randomly allocated to one of two inpatient treatment settings: a drug dependence unit with a special 10 week program and 4 weeks in a behavioural/general treatment unit without such a program. In each setting, following drug-withdrawal, subjects had either cue exposure for at least six sessions over 3 weeks, or a control condition. Subjects were followed up twice, at about 6 weeks and 6 months post-treatment. 186 subjects were randomly allocated; 69 were assessed post-detoxification, and of these 43 completed cue exposure or control treatments. Cue exposure and control subjects did not differ in cue reactivity. This was evaluated post-treatment for cue exposure subjects and at a comparable time point for controls. All groups showed a significant decrement in cue-elicited craving, withdrawal responses and negative mood. Cue exposure and control subjects did not differ at either of the two follow up interviews.",

keywords = "SMOKING CESSATION, SELF-EFFICACY, MANAGEMENT, ALCOHOLICS, DRINKING, RELAPSE, ABUSE",

author = "Sharon Dawe and Jane Powell and David Richards and Michael Gossop and Isaac Marks and John Strang and GRAY, {Jeffrey A}",

year = "1993",

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AU - Marks, Isaac

AU - Strang, John

AU - GRAY, Jeffrey A

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AB - A controlled trial studied whether cue exposure prevented relapse in opiate addiction. Subjects were randomly allocated to one of two inpatient treatment settings: a drug dependence unit with a special 10 week program and 4 weeks in a behavioural/general treatment unit without such a program. In each setting, following drug-withdrawal, subjects had either cue exposure for at least six sessions over 3 weeks, or a control condition. Subjects were followed up twice, at about 6 weeks and 6 months post-treatment. 186 subjects were randomly allocated; 69 were assessed post-detoxification, and of these 43 completed cue exposure or control treatments. Cue exposure and control subjects did not differ in cue reactivity. This was evaluated post-treatment for cue exposure subjects and at a comparable time point for controls. All groups showed a significant decrement in cue-elicited craving, withdrawal responses and negative mood. Cue exposure and control subjects did not differ at either of the two follow up interviews.

KW - SMOKING CESSATION

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KW - MANAGEMENT

KW - ALCOHOLICS

KW - DRINKING

KW - RELAPSE

KW - ABUSE

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