Doping in sport: 3. Metabolic conversion of oral norethisterone to urinary 19-norandrosterone

TY - JOUR

T1 - Doping in sport: 3. Metabolic conversion of oral norethisterone to urinary 19-norandrosterone

AU - Walker, Christopher J.

AU - Cowan, David A.

AU - James, Vivian H. T.

AU - Lau, Joanne C. Y.

AU - Kicman, Andrew T.

PY - 2009/3

Y1 - 2009/3

N2 - The detection of 19 norandrosterone (19-NA) in a competitor's urine sample is taken as prima facie evidence of administration of nandrolone or other 19-norsteroid but a potential problem is that administration of norethisterone, a progestogen used for menstrual disorders and for hormonal contraception, also results in the excretion of 19-NA that can exceed the laboratory reporting threshold of 2 ng/mL The contribution of norethisterone to urinary 19-NA with and without 19-norandrostenedione. a known norethisterone tablet impurity, requires evaluation. Preparations containing, either

AB - The detection of 19 norandrosterone (19-NA) in a competitor's urine sample is taken as prima facie evidence of administration of nandrolone or other 19-norsteroid but a potential problem is that administration of norethisterone, a progestogen used for menstrual disorders and for hormonal contraception, also results in the excretion of 19-NA that can exceed the laboratory reporting threshold of 2 ng/mL The contribution of norethisterone to urinary 19-NA with and without 19-norandrostenedione. a known norethisterone tablet impurity, requires evaluation. Preparations containing, either

U2 - 10.1016/j.steroids.2008.11.008

DO - 10.1016/j.steroids.2008.11.008

M3 - Article

VL - 74

SP - 341

EP - 349

JO - Steroids

JF - Steroids

IS - 3

ER -