Driving Cessation in Patients Attending a Young-Onset Dementia Clinic: A Retrospective Cohort Study

TY - JOUR

T1 - Driving Cessation in Patients Attending a Young-Onset Dementia Clinic

T2 - A Retrospective Cohort Study

AU - Velayudhan, Latha

AU - Baillon, Sarah

AU - Urbaskova, Gabriela

AU - McCulloch, Laura

AU - Tromans, Samuel

AU - Storey, Mathew

AU - Lindesay, James

AU - Bhattacharyya, Sagnik

PY - 2018

Y1 - 2018

N2 - Background: Although driving by persons with dementia is an important public health concern, little is known about driving cessation in younger people with dementia. We aimed to determine the prevalence and factors affecting driving cessation in individuals with and without dementia aged under 65 years attending a memory clinic in a European setting.Methods: Subjects were consecutive patients assessed at a specialist memory service at a university teaching hospital between 2000 and 2010. The data collected included demographic, clinical, standardized cognitive assessments as well as information on driving. Dementia diagnosis was made using ICD-10 criteria.Results: Of the 225 people who were or had been drivers, 32/79 (41%) with young-onset dementia (YOD) stopped driving compared to 25/146 (17%) patients who had cognitive impairment due to other causes. Women were more likely to cease driving and voluntarily than men (p < 0.001). Diagnosis of YOD was associated with driving cessation (1.193, 95% CI 0.570-1.815, p ≤ 0.001), and was mediated by impairment in praxis with the highest indirect mediation effect (0.754, 95% CI 0.183-1.401, p = 0.009).Conclusions: YOD diagnosis, female gender, and impairment in praxis have a higher probability for driving cessation in those under 65 years of age with cognitive impairment.

AB - Background: Although driving by persons with dementia is an important public health concern, little is known about driving cessation in younger people with dementia. We aimed to determine the prevalence and factors affecting driving cessation in individuals with and without dementia aged under 65 years attending a memory clinic in a European setting.Methods: Subjects were consecutive patients assessed at a specialist memory service at a university teaching hospital between 2000 and 2010. The data collected included demographic, clinical, standardized cognitive assessments as well as information on driving. Dementia diagnosis was made using ICD-10 criteria.Results: Of the 225 people who were or had been drivers, 32/79 (41%) with young-onset dementia (YOD) stopped driving compared to 25/146 (17%) patients who had cognitive impairment due to other causes. Women were more likely to cease driving and voluntarily than men (p < 0.001). Diagnosis of YOD was associated with driving cessation (1.193, 95% CI 0.570-1.815, p ≤ 0.001), and was mediated by impairment in praxis with the highest indirect mediation effect (0.754, 95% CI 0.183-1.401, p = 0.009).Conclusions: YOD diagnosis, female gender, and impairment in praxis have a higher probability for driving cessation in those under 65 years of age with cognitive impairment.

KW - Cognition

KW - Driving cessation

KW - Gender

KW - Young-onset dementia

UR - http://www.scopus.com/inward/record.url?scp=85046039059&partnerID=8YFLogxK

U2 - 10.1159/000488237

DO - 10.1159/000488237

M3 - Article

C2 - 29805385

AN - SCOPUS:85046039059

VL - 8

SP - 190

EP - 198

JO - Dementia and Geriatric Cognitive Disorders Extra

JF - Dementia and Geriatric Cognitive Disorders Extra

IS - 1

ER -