Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking

TY - JOUR

T1 - Drug reaction with eosinophilia and systemic symptoms (DRESS)

T2 - a clinical update and review of current thinking

AU - Walsh, S. A.

AU - Creamer, Daniel

PY - 2011/1

Y1 - 2011/1

N2 - Drug reaction with eosinophilia and systemic symptoms (DRESS) describes a severe medication-induced adverse reaction, which has cutaneous, haematological and solid-organ features. It is one of the triad of life-threatening drug hypersensitivity dermatoses, along with acute generalized exanthematous pustulosis (AGEP) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). In this article, we discuss several controversies that surround DRESS, including problems with nomenclature and the lack of consensus in diagnostic criteria.

AB - Drug reaction with eosinophilia and systemic symptoms (DRESS) describes a severe medication-induced adverse reaction, which has cutaneous, haematological and solid-organ features. It is one of the triad of life-threatening drug hypersensitivity dermatoses, along with acute generalized exanthematous pustulosis (AGEP) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). In this article, we discuss several controversies that surround DRESS, including problems with nomenclature and the lack of consensus in diagnostic criteria.

KW - ANTICONVULSANT-HYPERSENSITIVITY-SYNDROME

KW - STEVENS-JOHNSON-SYNDROME

KW - TOXIC EPIDERMAL NECROLYSIS

KW - HLA-B-ASTERISK-1502 ALLELE

KW - INDUCED PSEUDOLYMPHOMA

KW - CUTANEOUS REACTIONS

KW - ASSOCIATION

KW - HYPOGAMMAGLOBULINEMIA

KW - CYCLOSPORINE

KW - REACTIVATION

U2 - 10.1111/j.1365-2230.2010.03967.x

DO - 10.1111/j.1365-2230.2010.03967.x

M3 - Literature review

SN - 0307-6938

VL - 36

SP - 6

EP - 11

JO - Clinical and Experimental Dermatology

JF - Clinical and Experimental Dermatology

IS - 1

ER -