Drug use and associated neuropsychiatric conditions

Ashwin Venkataraman, Sam Turton, Anne Lingford-Hughes

Research output: Contribution to journalArticlepeer-review


Recreational drug use is a well-recognized problem of everyday society. Consumption seems to be driven and maintained for desired effects on cognitive or emotional states. ‘Drug use’ in some situations is seen as socially acceptable such as getting a caffeine ‘hit’ from a morning cup of coffee to ‘get going’ or drinking alcohol as part of a social occasion. However, for some individuals and for some substances, drug use risks adverse consequences for brain function and possible enduring harm. This chapter will focus on how brain function may be altered as a consequence of drug use and describe the current understanding of the neurobiology of drugs of abuse and how this may be related to neuropsychiatric consequences. Drugs can produce neuropsychiatric effects acutely during intoxication or withdrawal, and also after chronic exposure, with effects which may or may not be enduring with abstinence.
Original languageEnglish
Pages (from-to)329–340
JournalOxford Textbook of Neuropsychiatry
Publication statusPublished - Aug 2020


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