Duration of untreated prodromal symptoms and 12-month functional outcome of individuals at risk of psychosis

TY - JOUR

T1 - Duration of untreated prodromal symptoms and 12-month functional outcome of individuals at risk of psychosis

AU - Fusar-Poli, P.

AU - Meneghelli, A.

AU - Valmaggia, L.

AU - Allen, P.

AU - Galvan, F.

AU - McGuire, P.

AU - Cocchi, A.

PY - 2009/2

Y1 - 2009/2

N2 - Individuals seeking help from prodromal services may have been experiencing attenuated psychotic features and psychosocial impairments for a long period prior to referral. The effect of an extended duration of these untreated 'at risk' symptoms on patients' long-term functional outcome was assessed in a 12-month longitudinal observational study (n=49). A longer duration of untreated 'at risk' symptoms was correlated with a reduced improvement in Global Assessment of Functioning scores after 12 months (beta=-0.375, P=0.008). This effect was independent of age and gender and may have implications for the improvement of treatment strategies in pre-psychotic phases.

AB - Individuals seeking help from prodromal services may have been experiencing attenuated psychotic features and psychosocial impairments for a long period prior to referral. The effect of an extended duration of these untreated 'at risk' symptoms on patients' long-term functional outcome was assessed in a 12-month longitudinal observational study (n=49). A longer duration of untreated 'at risk' symptoms was correlated with a reduced improvement in Global Assessment of Functioning scores after 12 months (beta=-0.375, P=0.008). This effect was independent of age and gender and may have implications for the improvement of treatment strategies in pre-psychotic phases.

U2 - 10.1192/bjp.bp.107.047951

DO - 10.1192/bjp.bp.107.047951

M3 - Article

SN - 1472-1465

VL - 194

SP - 181

EP - 182

JO - British Journal of Psychiatry

JF - British Journal of Psychiatry

IS - 2

ER -