Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders

Kristelle Hudry; Susie Chandler; Rachael Bedford; Greg Pasco; Teodora Gliga; Mayada Elsabbagh; Mark H. Johnson; Tony Charman

doi:10.1007/s10803-013-1861-4

Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders

Kristelle Hudry^*, Susie Chandler, Rachael Bedford, Greg Pasco, Teodora Gliga, Mayada Elsabbagh, Mark H. Johnson, Tony Charman

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.

Original language	English
Pages (from-to)	154-167
Number of pages	14
Journal	Journal of Autism and Developmental Disorders
Volume	44
Issue number	1
DOIs	https://doi.org/10.1007/s10803-013-1861-4
Publication status	Published - Jan 2014

Keywords

Autism spectrum disorder
Broader autism phenotype
High-risk siblings
Receptive language
Expressive language
Language profiles
COMMUNICATIVE DEVELOPMENT
CHILDREN
PRESCHOOLERS
IMPAIRMENT
VOCABULARY
ABILITIES
TODDLERS

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@article{287398506b2844bc81b356a294ca0e8e,

title = "Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders",

abstract = "Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.",

keywords = "Autism spectrum disorder, Broader autism phenotype, High-risk siblings, Receptive language, Expressive language, Language profiles, COMMUNICATIVE DEVELOPMENT, CHILDREN, PRESCHOOLERS, IMPAIRMENT, VOCABULARY, ABILITIES, TODDLERS",

author = "Kristelle Hudry and Susie Chandler and Rachael Bedford and Greg Pasco and Teodora Gliga and Mayada Elsabbagh and Johnson, {Mark H.} and Tony Charman",

year = "2014",

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doi = "10.1007/s10803-013-1861-4",

language = "English",

volume = "44",

pages = "154--167",

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TY - JOUR

T1 - Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders

AU - Hudry, Kristelle

AU - Chandler, Susie

AU - Bedford, Rachael

AU - Pasco, Greg

AU - Gliga, Teodora

AU - Elsabbagh, Mayada

AU - Johnson, Mark H.

AU - Charman, Tony

PY - 2014/1

Y1 - 2014/1

N2 - Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.

AB - Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.

KW - Autism spectrum disorder

KW - Broader autism phenotype

KW - High-risk siblings

KW - Receptive language

KW - Expressive language

KW - Language profiles

KW - COMMUNICATIVE DEVELOPMENT

KW - CHILDREN

KW - PRESCHOOLERS

KW - IMPAIRMENT

KW - VOCABULARY

KW - ABILITIES

KW - TODDLERS

U2 - 10.1007/s10803-013-1861-4

DO - 10.1007/s10803-013-1861-4

M3 - Article

SN - 0162-3257

VL - 44

SP - 154

EP - 167

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

IS - 1

ER -

Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders

Abstract

Keywords

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