King's College London

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial

Di, W. L., Lwin, S. M., Petrova, A., Bernadis, C., Syed, F., Farzaneh, F., Moulding, D., Martinez, A. E., Sebire, N. J., Rampling, D., Virasami, A., Zamiri, M., Wang, W., Hara, H., Kadiyirire, T., Abdul-Wahab, A., Martinez-Queipo, M., Harper, J. I., McGrath, J. A., Thrasher, A. J., & 2 othersMellerio, J. E. & Qasim, W., 17 Sep 2019, In: Human Gene Therapy. 30, 9, p. 1067-1078 12 p.

Research output: Contribution to journal › Article › peer-review

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa

Lwin, S. M., Syed, F., Di, W., Kadiyirire, T., Liu, L., Guy, A., Petrova, A., Abdul-Wahab, A., Reid, F., Phillips, R., Elstad, M., Georgiadis, C., Aristodemou, S., Lovell, P. A., Mcmillan, J. R., Mee, J., Miskinyte, S., Titeux, M., Ozoemena, L., Pramanik, R., & 21 othersSerrano, S., Rowles, R., Maurin, C., Orrin, E., Martinez-Queipo, M., Rashidghamat, E., Tziotzios, C., Onoufriadis, A., Chen, M., Chan, L., Farzaneh, F., Del Rio, M., Tolar, J., Bauer, J. W., Larcher, F., Antoniou, M. N., Hovnanian, A., Thrasher, A. J., Mellerio, J. E., Qasim, W. & Mcgrath, J. A., 6 Jun 2019, In: JCI Insight. 4, 11, :e126243.

Research output: Contribution to journal › Article › peer-review

227 Patient pre-selection outcomes for the European GENEGRAFT ex vivo phase I/II gene therapy trial for recessive dystrophic epidermolysis bullosa: ESDR 2017 Annual Meeting47th Annual ESDR Meeting

Lwin, S. M., Gaucher, S., Titeux, M., Abdul-Wahab, A., Pironon, N., Miskinyte, S., GANIER, C., Duchatelet, S., McGrath, J. & Hovnanian, A., 8 Sep 2017, (E-pub ahead of print) In: Journal of Investigative Dermatology. 137, 10, Supplement 2, p. S231

Research output: Contribution to journal › Article › peer-review

Potential of Systemic Allogeneic Mesenchymal Stromal Cell Therapy for Children with Recessive Dystrophic Epidermolysis Bullosa

Petrof, G., Lwin, S. M., Martinez-Queipo, M., Abdul-Wahab, A., Tso, S., Mellerio, J. E., Slaper-Cortenbach, I., Boelens, J. J., Tolar, J., Veys, P., Ofuya, M., Peacock, J., Martinez, A. E. & McGrath, J. A., 30 Sep 2015, In: Journal of Investigative Dermatology. 135, 9, p. 2319-2321

Research output: Contribution to journal › Letter › peer-review

Lentiviral Engineered Fibroblasts Expressing Codon Optimized COL7A1 Restore Anchoring Fibrils in RDEB

Georgiadis, C., Syed, F., Petrova, A., Abdul-Wahab, A., Lwin, S. M., Farzaneh, F., Chan, L., Ghani, S., Fleck, R. A., Glover, L., McMillan, J. R., Chen, M., Thrasher, A. J., McGrath, J. A., Di, W-L. & Qasim, W., 22 Sep 2015, (E-pub ahead of print) In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Loss of RhoE function in dermatofibroma promotes disorganized dermal fibroblast extracellular matrix and increased integrin activation

Endzhievskaya, S., Hsu, C-K., Yang, H-S., Huang, H-Y., Lin, Y-C., Lee, J. Y. W., Onoufriadis, A., Takeichi, T., Lee, J. Y-Y., Shaw, T., McGrath, J. & Parsons, M., 31 Jan 2023, (Accepted/In press) In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Comorbidities of keloid and hypertrophic scars in UK Biobank: Comorbidities of excessive scarring

Ung, C. Y., Warwick, A. N., Onoufriadis, A., Barker, J., Parsons, M., McGrath, J., Shaw, T. & Dand, N., 4 Jan 2023, In: JAMA dermatology.

Research output: Contribution to journal › Article › peer-review

Plasma metabolomic profiling reflects the malnourished and chronic inflammatory state in recessive dystrophic epidermolysis bullosa

Chen, Y. F., Lu, H. C., Hou, P. C., Lin, Y. C., Aala, W., Onoufriadis, A., McGrath, J. A., Chen, Y. L. & Hsu, C. K., Aug 2022, In: Journal of Dermatological Science. 107, 2, p. 82-88 7 p.

Research output: Contribution to journal › Article › peer-review

Autosomal dominant epidermolysis bullosa simplex exacerbated by hyperkeratotic scabies

Lin, Y. C., Tu, W. T., Hou, P. C., Huang, H. Y., Chen, P. C., Chang, C. H., Lee, J. Y. Y., McGrath, J. A. & Hsu, C. K., Aug 2022, In: Journal of Dermatology. 49, 8, p. e283-e284

Research output: Contribution to journal › Letter › peer-review

Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo

Cao, Q., Tartaglia, G., Alexander, M., Park, P. H., Poojan, S., Farshchian, M., Fuentes, I., Chen, M., McGrath, J. A., Palisson, F., Salas-Alanis, J. & South, A. P., Aug 2022, In: Matrix Biology. 111, p. 226-244 19 p.

Research output: Contribution to journal › Article › peer-review

Dapsone therapy for Hidradenitis Suppurativa: a retrospective review of characteristics and treatment outcomes in a cohort of 122 patients in a tertiary dermatology setting

Steyn, M., Ayis, S., O'Connor, J., Kaur Lakhan, M., Ferguson, F., Shah, A. & Rashidghamat, E., 7 Dec 2022, In: British Journal of Dermatology. BJD

Research output: Contribution to journal › Article › peer-review

Germline intergenic duplications at Xq26.1 underlie Bazex–Dupré–Christol basal cell carcinoma susceptibility syndrome

Liu, Y., Banka, S., Huang, Y., Hardman-Smart, J., Pye, D., Torrelo, A., Beaman, G. M., Kazanietz, M. G., Baker, M. J., Ferrazzano, C., Shi, C., Orozco, G., Eyre, S., van Geel, M., Bygum, A., Fischer, J., Miedzybrodzka, Z., Abuzahra, F., Rübben, A., Cuvertino, S., & 12 othersEllingford, J. M., Smith, M. J., Evans, D. G., Weppner-Parren, L. J. M. T., van Steensel, M. A. M., Chaudhary, I. H., Mangham, D. C., Lear, J. T., Paus, R., Frank, J., Newman, W. G. & Zhang, X., Dec 2022, In: British Journal of Dermatology. 187, 6, p. 948-961 14 p.

Research output: Contribution to journal › Article › peer-review

Cutaneous Manifestations of SARS-CoV-2 infection during the Delta and Omicron waves in 348,691 UK users of the UK ZOE COVID Study App

Visconti, A., Murray, B., Rossi, N., Wolf, J., Ourselin, S., Spector, T. D., Freeman, E. E., Bataille, V. & Falchi, M., Dec 2022, In: The British journal of dermatology. 187, 6, p. 900-908 9 p.

Research output: Contribution to journal › Article › peer-review

Biomarkers of systemic treatment response in people with psoriasis: a scoping review

Corbett, M., Ramessur, R., Marshall, D., Acencio, M., Ostaszewski, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Barker, J., Ndlovu, M., & 3 othersConrad, C., Skov, L. & Smith, C., Oct 2022, In: British Journal of Dermatology. 187, 4, p. 494-506 13 p.

Research output: Contribution to journal › Article › peer-review

Biomarkers of disease progression in people with psoriasis: a scoping review

Ramessur, R., Corbett, M., Marshall, D., Acencio, M., Biscaia De Andrade Barbosa, I., Dand, N., Di Meglio, P., Haddad, S., Jensen, A., Koopmann, W., Mahil, S., Ostaszewski, M., Rahmatulla, S., Rastrick, J., Saklatvala, J., Weidinger, S., Wright, K., Eyerich, K., Ndlovu, M., Barker, J., & 3 othersSkov, L., Conrad, C. & Smith, C., Oct 2022, In: British Journal of Dermatology. 187, 4, p. 481-493 13 p.

Research output: Contribution to journal › Review article › peer-review