EEG, behavioural and physiological recordings following a painful procedure in human neonates

Laura Jones; Maria Pureza Laudiano-Dray; Kimberley Whitehead; Madeleine Verriotis; Judith Meek; Maria Fitzgerald; Lorenzo Fabrizi

doi:10.1038/sdata.2018.248

EEG, behavioural and physiological recordings following a painful procedure in human neonates

Laura Jones, Maria Pureza Laudiano-Dray, Kimberley Whitehead, Madeleine Verriotis, Judith Meek, Maria Fitzgerald, Lorenzo Fabrizi

Digital Health & Applied Tech Assessment

Univ London, Birkbeck University London, University College London, University of London Royal Veterinary College, University of London, St Georges University London, Imperial College London, Kings College London, Royal Holloway University London, Queen Mary University London, Div Populat Hlth Sci & Educ
UCL Hospitals NHS Foundation Trust

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

We present a dataset of cortical, behavioural, and physiological responses following a single, clinically required noxious stimulus in a neonatal sample. Cortical activity was recorded from 112 neonates (29-47 weeks gestational age at study) using a 20-channel electroencephalogram (EEG), which was time-locked to a heel lance. This data is linked to pain-related behaviour (facial expression), physiology (heart rate, oxygenation) and a composite clinical score (Premature Infant Pain Profile, PIPP). The dataset includes responses to non-noxious sham and auditory controls. The infants' relevant medical and pain history was collected up to the day of the study and recorded in an extensive database of variables including clinical condition at birth, diagnoses, medications, previous painful procedures, injuries, and selected maternal information. This dataset can be used to investigate the cortical, physiological, and behavioural pain-related processing in human infants and to evaluate the impact of medical conditions and experiences upon the infant response to noxious stimuli. Furthermore, it provides information on the formation of individual pain phenotypes.

Original language	English
Pages (from-to)	180248
Journal	Scientific Data
Volume	5
DOIs	https://doi.org/10.1038/sdata.2018.248
Publication status	Published - 13 Nov 2018

Keywords

Electroencephalography/methods
Facial Expression
Humans
Infant, Newborn/physiology
Infant, Premature
Nociception
Pain/physiopathology
Pain Measurement

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10.1038/sdata.2018.248

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title = "EEG, behavioural and physiological recordings following a painful procedure in human neonates",

abstract = "We present a dataset of cortical, behavioural, and physiological responses following a single, clinically required noxious stimulus in a neonatal sample. Cortical activity was recorded from 112 neonates (29-47 weeks gestational age at study) using a 20-channel electroencephalogram (EEG), which was time-locked to a heel lance. This data is linked to pain-related behaviour (facial expression), physiology (heart rate, oxygenation) and a composite clinical score (Premature Infant Pain Profile, PIPP). The dataset includes responses to non-noxious sham and auditory controls. The infants' relevant medical and pain history was collected up to the day of the study and recorded in an extensive database of variables including clinical condition at birth, diagnoses, medications, previous painful procedures, injuries, and selected maternal information. This dataset can be used to investigate the cortical, physiological, and behavioural pain-related processing in human infants and to evaluate the impact of medical conditions and experiences upon the infant response to noxious stimuli. Furthermore, it provides information on the formation of individual pain phenotypes.",

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T1 - EEG, behavioural and physiological recordings following a painful procedure in human neonates

AU - Jones, Laura

AU - Laudiano-Dray, Maria Pureza

AU - Whitehead, Kimberley

AU - Verriotis, Madeleine

AU - Meek, Judith

AU - Fitzgerald, Maria

AU - Fabrizi, Lorenzo

PY - 2018/11/13

Y1 - 2018/11/13

N2 - We present a dataset of cortical, behavioural, and physiological responses following a single, clinically required noxious stimulus in a neonatal sample. Cortical activity was recorded from 112 neonates (29-47 weeks gestational age at study) using a 20-channel electroencephalogram (EEG), which was time-locked to a heel lance. This data is linked to pain-related behaviour (facial expression), physiology (heart rate, oxygenation) and a composite clinical score (Premature Infant Pain Profile, PIPP). The dataset includes responses to non-noxious sham and auditory controls. The infants' relevant medical and pain history was collected up to the day of the study and recorded in an extensive database of variables including clinical condition at birth, diagnoses, medications, previous painful procedures, injuries, and selected maternal information. This dataset can be used to investigate the cortical, physiological, and behavioural pain-related processing in human infants and to evaluate the impact of medical conditions and experiences upon the infant response to noxious stimuli. Furthermore, it provides information on the formation of individual pain phenotypes.

AB - We present a dataset of cortical, behavioural, and physiological responses following a single, clinically required noxious stimulus in a neonatal sample. Cortical activity was recorded from 112 neonates (29-47 weeks gestational age at study) using a 20-channel electroencephalogram (EEG), which was time-locked to a heel lance. This data is linked to pain-related behaviour (facial expression), physiology (heart rate, oxygenation) and a composite clinical score (Premature Infant Pain Profile, PIPP). The dataset includes responses to non-noxious sham and auditory controls. The infants' relevant medical and pain history was collected up to the day of the study and recorded in an extensive database of variables including clinical condition at birth, diagnoses, medications, previous painful procedures, injuries, and selected maternal information. This dataset can be used to investigate the cortical, physiological, and behavioural pain-related processing in human infants and to evaluate the impact of medical conditions and experiences upon the infant response to noxious stimuli. Furthermore, it provides information on the formation of individual pain phenotypes.

KW - Electroencephalography/methods

KW - Facial Expression

KW - Humans

KW - Infant, Newborn/physiology

KW - Infant, Premature

KW - Nociception

KW - Pain/physiopathology

KW - Pain Measurement

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DO - 10.1038/sdata.2018.248

M3 - Article

C2 - 30422128

VL - 5

SP - 180248

JO - Scientific Data

JF - Scientific Data

ER -

EEG, behavioural and physiological recordings following a painful procedure in human neonates

Abstract

Keywords

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