King's College London

Research portal

Effect of antioxidant/reducing agents on the initial and long-term bonding performance of a self-etch adhesive to caries-affected dentin with and without smear layer-deproteinizing

Research output: Contribution to journalArticle

Taweesak Prasansuttiporn, Ornnicha Thanatvarakorn, Teerapong Mamanee, Keiichi Hosaka, Junji Tagami, Richard M. Foxton, Masatoshi Nakajima

Original languageEnglish
Article number102648
JournalINTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES
Volume102
DOIs
Publication statusPublished - Oct 2020

King's Authors

Abstract

This study aimed to evaluate the effect of a reducing agent containing p-toluenesulfinic acid sodium salt (Accel®) and plant-extract antioxidant (rosmarinic acid solution) on the bonding durability of a self-etch adhesive to caries-affected dentin with and without smear layer-deproteinizing with NaOCl solution. The caries-affected dentin were assigned to pretreatment of smear layer-deproteinizing with NaOCl solution or none, then subdivided to reducing agent/antioxidant treatment with p-toluenesulfinic acid sodium salt or rosmarinic acid solution or none. After bonding with 2-step self-etch adhesive and restoring with resin composite, the specimens were stored in artificial saliva for 24 h or 1 year. The microtensile bond strength (μTBS) were analyzed by three-way ANOVA with post-hoc Tukey's test and t-test (p < 0.05). The collagen-fibril status at hybridized complex was observed under TEM. The results showed that μTBS to caries-affected dentin significantly decreased after 1-year of storage (p < 0.05). Smear layer-deproteinizing with NaOCl significantly decreased μTBS to caries-affected dentin despite eliminating hybridized smear layer, however a subsequent application with p-toluenesulfinic acid sodium salt and rosmarinic acid solution significantly increased initial bond strengths (p < 0.05) and maintained the bond strengths after 1-year of storage (p > 0.05), with preservation of collagen-fibril integrity within authentic hybrid layer. Therefore, the additional application of p-toluenesulfinic acid sodium salt and rosmarinic acid solution after smear layer-deproteinizing with NaOCl could improve initial and long-term bond strengths of a self-etch adhesive to caries-affected dentin.

View graph of relations

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454