TY - CHAP
T1 - Effects of transcranial stimulation in developmental neurocognitive disorders
T2 - A critical appraisal
AU - Santos, Flavia H.
AU - Mosbacher, Jochen A.
AU - Menghini, Deny
AU - Rubia, Katya
AU - Grabner, Roland H.
AU - Cohen Kadosh, Roi
N1 - Funding Information:
The research was partly funded by the Austrian Science Fund (FWF; Project number: P30050-GBL). The FWF was not involved in study planning, data collection, analysis and interpretation, writing, or publishing.
Publisher Copyright:
© 2021 Elsevier B.V.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/6/21
Y1 - 2021/6/21
N2 - Non-invasive brain stimulation (NIBS) has been highlighted as a powerful tool to promote neuroplasticity, and an attractive approach to support cognitive remediation. Here we provide a systematic review of 26 papers using NIBS to ameliorate cognitive dysfunctions in three prevalent neurodevelopmental disorders: Attention-Deficit/Hyperactivity Disorder (ADHD), Developmental Dyslexia and Developmental Dyscalculia. An overview of the state of research shows a predominance of studies using repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) techniques, and an unequal distribution among clinical conditions. Regarding the utility of NIBS, the results are promising but also ambiguous. Twenty-three papers reported beneficial effects, but many of these effects were found only once or were only partially replicated and some studies even reported detrimental effects. Furthermore, most studies differed in at least one core aspect, the NIBS applied, the questionnaires and cognitive tests conducted, or the age group investigated, and sample sizes were mostly small. Hence, further studies are needed to rigorously examine the potential of NIBS in the remediation of cognitive functions. Finally, we discuss potential caveats and future directions. We reason that if adequately addressing these challenges NIBS can be feasible, with potential benefits in treating neurodevelopmental disorders.
AB - Non-invasive brain stimulation (NIBS) has been highlighted as a powerful tool to promote neuroplasticity, and an attractive approach to support cognitive remediation. Here we provide a systematic review of 26 papers using NIBS to ameliorate cognitive dysfunctions in three prevalent neurodevelopmental disorders: Attention-Deficit/Hyperactivity Disorder (ADHD), Developmental Dyslexia and Developmental Dyscalculia. An overview of the state of research shows a predominance of studies using repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) techniques, and an unequal distribution among clinical conditions. Regarding the utility of NIBS, the results are promising but also ambiguous. Twenty-three papers reported beneficial effects, but many of these effects were found only once or were only partially replicated and some studies even reported detrimental effects. Furthermore, most studies differed in at least one core aspect, the NIBS applied, the questionnaires and cognitive tests conducted, or the age group investigated, and sample sizes were mostly small. Hence, further studies are needed to rigorously examine the potential of NIBS in the remediation of cognitive functions. Finally, we discuss potential caveats and future directions. We reason that if adequately addressing these challenges NIBS can be feasible, with potential benefits in treating neurodevelopmental disorders.
KW - Attention-deficit/hyperactivity disorder
KW - Developmental dyscalculia
KW - Developmental dyslexia
KW - Developmental neurocognitive disorders
KW - Non-invasive brain stimulation
UR - http://www.scopus.com/inward/record.url?scp=85104116082&partnerID=8YFLogxK
U2 - 10.1016/bs.pbr.2021.01.012
DO - 10.1016/bs.pbr.2021.01.012
M3 - Chapter
AN - SCOPUS:85104116082
SN - 9780128223444
T3 - Progress in Brain Research
SP - 1
EP - 40
BT - Non-invasive Brain Stimulation (NIBS) in Neurodevelopmental Disorders
A2 - Kadosh, Roi Cohen
A2 - Zaehle, Tino
A2 - Krauel, Kerstin
PB - Elsevier B.V.
ER -