Endogenous Labeling for Light Microscopy during HIV-1 Immune Responses

Minette Salmon; Irene Carlon-Andres; Sergi Padilla-Parra

doi:10.1016/j.it.2020.10.009

Endogenous Labeling for Light Microscopy during HIV-1 Immune Responses

Minette Salmon, Irene Carlon-Andres, Sergi Padilla-Parra^*

^*Corresponding author for this work

Infectious Diseases

Research output: Contribution to journal › Short survey › peer-review

Abstract

New approaches in single molecule spectroscopy and microscopy are able to resolve the spatial and temporal resolution of T cell receptor signaling in the context of immune responses to HIV-1 infection. These approaches need to be complemented with novel techniques that endogenously tag the protein or proteins of interest, yet avoid overexpression, to image protein dynamics under physiological conditions.

Original language	English
Pages (from-to)	1056-1059
Number of pages	4
Journal	TRENDS IN IMMUNOLOGY
Volume	41
Issue number	12
DOIs	https://doi.org/10.1016/j.it.2020.10.009
Publication status	Published - Dec 2020

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10.1016/j.it.2020.10.009

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title = "Endogenous Labeling for Light Microscopy during HIV-1 Immune Responses",

abstract = "New approaches in single molecule spectroscopy and microscopy are able to resolve the spatial and temporal resolution of T cell receptor signaling in the context of immune responses to HIV-1 infection. These approaches need to be complemented with novel techniques that endogenously tag the protein or proteins of interest, yet avoid overexpression, to image protein dynamics under physiological conditions.",

author = "Minette Salmon and Irene Carlon-Andres and Sergi Padilla-Parra",

year = "2020",

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language = "English",

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TY - JOUR

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AU - Salmon, Minette

AU - Carlon-Andres, Irene

AU - Padilla-Parra, Sergi

PY - 2020/12

Y1 - 2020/12

N2 - New approaches in single molecule spectroscopy and microscopy are able to resolve the spatial and temporal resolution of T cell receptor signaling in the context of immune responses to HIV-1 infection. These approaches need to be complemented with novel techniques that endogenously tag the protein or proteins of interest, yet avoid overexpression, to image protein dynamics under physiological conditions.

AB - New approaches in single molecule spectroscopy and microscopy are able to resolve the spatial and temporal resolution of T cell receptor signaling in the context of immune responses to HIV-1 infection. These approaches need to be complemented with novel techniques that endogenously tag the protein or proteins of interest, yet avoid overexpression, to image protein dynamics under physiological conditions.

UR - http://www.scopus.com/inward/record.url?scp=85096376657&partnerID=8YFLogxK

U2 - 10.1016/j.it.2020.10.009

DO - 10.1016/j.it.2020.10.009

M3 - Short survey

C2 - 33148466

AN - SCOPUS:85096376657

SN - 1471-4906

VL - 41

SP - 1056

EP - 1059

JO - TRENDS IN IMMUNOLOGY

JF - TRENDS IN IMMUNOLOGY

IS - 12

ER -

Endogenous Labeling for Light Microscopy during HIV-1 Immune Responses

Abstract

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