King's College London

Research portal

Endogenous Labeling for Light Microscopy during HIV-1 Immune Responses

Research output: Contribution to journalShort surveypeer-review

Minette Salmon, Irene Carlon-Andres, Sergi Padilla-Parra

Original languageEnglish
Pages (from-to)1056-1059
Number of pages4
JournalTRENDS IN IMMUNOLOGY
Volume41
Issue number12
DOIs
PublishedDec 2020

King's Authors

Abstract

New approaches in single molecule spectroscopy and microscopy are able to resolve the spatial and temporal resolution of T cell receptor signaling in the context of immune responses to HIV-1 infection. These approaches need to be complemented with novel techniques that endogenously tag the protein or proteins of interest, yet avoid overexpression, to image protein dynamics under physiological conditions.

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454