Endogenous opioid release in the human brain reward system induced by acute amphetamine administration

Alessandro Colasanti; Graham E Searle; Christopher J Long; Samuel P Hill; Richard R Reiley; Darren Quelch; David Erritzoe; Andri C Tziortzi; Laurence J Reed; Anne R Lingford-Hughes; Adam D Waldman; Koen R J Schruers; Paul M Matthews; Roger N Gunn; David J Nutt; Eugenii Rabiner

doi:10.1016/j.biopsych.2012.01.027

Endogenous opioid release in the human brain reward system induced by acute amphetamine administration

Alessandro Colasanti, Graham E Searle, Christopher J Long, Samuel P Hill, Richard R Reiley, Darren Quelch, David Erritzoe, Andri C Tziortzi, Laurence J Reed, Anne R Lingford-Hughes, Adam D Waldman, Koen R J Schruers, Paul M Matthews, Roger N Gunn, David J Nutt, Eugenii Rabiner

Research output: Contribution to journal › Article › peer-review

102 Citations (Scopus)

Abstract

We aimed to demonstrate a pharmacologically stimulated endogenous opioid release in the living human brain by evaluating the effects of amphetamine administration on [(11)C]carfentanil binding with positron emission tomography (PET).

Original language	English
Pages (from-to)	371-377
Number of pages	7
Journal	Biological psychiatry
Volume	72
Issue number	5
DOIs	https://doi.org/10.1016/j.biopsych.2012.01.027
Publication status	Published - 2012

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Colasanti, A., Searle, G. E., Long, C. J., Hill, S. P., Reiley, R. R., Quelch, D., Erritzoe, D., Tziortzi, A. C., Reed, L. J., Lingford-Hughes, A. R., Waldman, A. D., Schruers, K. R. J., Matthews, P. M., Gunn, R. N., Nutt, D. J., & Rabiner, E. (2012). Endogenous opioid release in the human brain reward system induced by acute amphetamine administration. Biological psychiatry, 72(5), 371-377. https://doi.org/10.1016/j.biopsych.2012.01.027

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title = "Endogenous opioid release in the human brain reward system induced by acute amphetamine administration",

abstract = "We aimed to demonstrate a pharmacologically stimulated endogenous opioid release in the living human brain by evaluating the effects of amphetamine administration on [(11)C]carfentanil binding with positron emission tomography (PET).",

author = "Alessandro Colasanti and Searle, {Graham E} and Long, {Christopher J} and Hill, {Samuel P} and Reiley, {Richard R} and Darren Quelch and David Erritzoe and Tziortzi, {Andri C} and Reed, {Laurence J} and Lingford-Hughes, {Anne R} and Waldman, {Adam D} and Schruers, {Koen R J} and Matthews, {Paul M} and Gunn, {Roger N} and Nutt, {David J} and Eugenii Rabiner",

year = "2012",

doi = "10.1016/j.biopsych.2012.01.027",

language = "English",

volume = "72",

pages = "371--377",

journal = "Biological psychiatry",

issn = "0006-3223",

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Colasanti, A, Searle, GE, Long, CJ, Hill, SP, Reiley, RR, Quelch, D, Erritzoe, D, Tziortzi, AC, Reed, LJ, Lingford-Hughes, AR, Waldman, AD, Schruers, KRJ, Matthews, PM, Gunn, RN, Nutt, DJ & Rabiner, E 2012, 'Endogenous opioid release in the human brain reward system induced by acute amphetamine administration', Biological psychiatry, vol. 72, no. 5, pp. 371-377. https://doi.org/10.1016/j.biopsych.2012.01.027

TY - JOUR

T1 - Endogenous opioid release in the human brain reward system induced by acute amphetamine administration

AU - Colasanti, Alessandro

AU - Searle, Graham E

AU - Long, Christopher J

AU - Hill, Samuel P

AU - Reiley, Richard R

AU - Quelch, Darren

AU - Erritzoe, David

AU - Tziortzi, Andri C

AU - Reed, Laurence J

AU - Lingford-Hughes, Anne R

AU - Waldman, Adam D

AU - Schruers, Koen R J

AU - Matthews, Paul M

AU - Gunn, Roger N

AU - Nutt, David J

AU - Rabiner, Eugenii

PY - 2012

Y1 - 2012

N2 - We aimed to demonstrate a pharmacologically stimulated endogenous opioid release in the living human brain by evaluating the effects of amphetamine administration on [(11)C]carfentanil binding with positron emission tomography (PET).

AB - We aimed to demonstrate a pharmacologically stimulated endogenous opioid release in the living human brain by evaluating the effects of amphetamine administration on [(11)C]carfentanil binding with positron emission tomography (PET).

U2 - 10.1016/j.biopsych.2012.01.027

DO - 10.1016/j.biopsych.2012.01.027

M3 - Article

C2 - 22386378

SN - 0006-3223

VL - 72

SP - 371

EP - 377

JO - Biological psychiatry

JF - Biological psychiatry

IS - 5

ER -

Endogenous opioid release in the human brain reward system induced by acute amphetamine administration

Abstract

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