Endogenous opioid release in the human brain reward system induced by acute amphetamine administration

Alessandro Colasanti, Graham E Searle, Christopher J Long, Samuel P Hill, Richard R Reiley, Darren Quelch, David Erritzoe, Andri C Tziortzi, Laurence J Reed, Anne R Lingford-Hughes, Adam D Waldman, Koen R J Schruers, Paul M Matthews, Roger N Gunn, David J Nutt, Eugenii Rabiner

Research output: Contribution to journalArticlepeer-review

90 Citations (Scopus)

Abstract

We aimed to demonstrate a pharmacologically stimulated endogenous opioid release in the living human brain by evaluating the effects of amphetamine administration on [(11)C]carfentanil binding with positron emission tomography (PET).
Original languageEnglish
Pages (from-to)371-377
Number of pages7
JournalBiological psychiatry
Volume72
Issue number5
DOIs
Publication statusPublished - 2012

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