Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology

Silvia Crescioli, Giulia Chiaruttini, Silvia Mele, Kristina M Ilieva, Giulia Pellizzari, Daniel I R Spencer, Richard A Gardner, Katie E Lacy, James F Spicer, Andrew N J Tutt, Gerd K Wagner, Sophia N Karagiannis*

*Corresponding author for this work

Research output: Contribution to journalLetterpeer-review

19 Citations (Scopus)
321 Downloads (Pure)

Abstract

We developed a versatile, novel, time- and resource-effective tool for production of functional IgE at high yields that has wide application potential in basic research and clinical evaluations in allergy, cancer immunotherapy and AllergoOncology.

Original languageEnglish
Pages (from-to)1519-1523
Number of pages5
JournalJournal of Allergy and Clinical Immunology
Volume141
Issue number4
Early online date19 Jan 2018
DOIs
Publication statusPublished - 1 Apr 2018

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