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Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology

Research output: Contribution to journalLetter

Silvia Crescioli, Giulia Chiaruttini, Silvia Mele, Kristina M Ilieva, Giulia Pellizzari, Daniel I R Spencer, Richard A Gardner, Katie E Lacy, James F Spicer, Andrew N J Tutt, Gerd K Wagner, Sophia N Karagiannis

Original languageEnglish
Pages (from-to)1519-1523
Number of pages5
JournalJournal of Allergy and Clinical Immunology
Early online date19 Jan 2018
DOIs
Accepted/In press18 Dec 2017
E-pub ahead of print19 Jan 2018
Published1 Apr 2018

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King's Authors

Abstract

We developed a versatile, novel, time- and resource-effective tool for production of functional IgE at high yields that has wide application potential in basic research and clinical evaluations in allergy, cancer immunotherapy and AllergoOncology.

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