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Erythroleukemia: all roads lead to GATA1?

Research output: Contribution to journalReview article

Original languageEnglish
Pages (from-to)648-649
Number of pages2
JournalBlood
Volume136
Issue number6
DOIs
Published6 Aug 2020

King's Authors

Abstract

In this issue of Blood, Fagnan et al investigate the genetic and transcriptional landscape of 33 acute erythroleukemia (AEL) patients and propose a transcriptome-based space that helps distinguish AEL from other myeloid leukemias. 1 They also provide intriguing evidence for leukemic transformation in AEL being a result of aberrant transcription factor expression impinging on GATA1 functions in erythropoiesis.

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