Escherichia coli cytotoxic necrotizing factor and Pasteurella multocida toxin induce focal adhesion kinase autophosphorylation and Src association

TY - JOUR

T1 - Escherichia coli cytotoxic necrotizing factor and Pasteurella multocida toxin induce focal adhesion kinase autophosphorylation and Src association

AU - Thomas, W

AU - Pullinger, G D

AU - Lax, A J

AU - Rozengurt, E

PY - 2001

Y1 - 2001

N2 - Cytotoxic necrotizing factor 1 and Pasteurella multocida toxin induced dose- and time-dependent increases in focal adhesion kinase (FAK) Tyr(397) phosphorylation in Swiss 3T3 cells. FAK autophosphorylation was sensitive to inhibitors of p160/ROCK and coincided with the formation of stable complexes between FAK and Src family members.

AB - Cytotoxic necrotizing factor 1 and Pasteurella multocida toxin induced dose- and time-dependent increases in focal adhesion kinase (FAK) Tyr(397) phosphorylation in Swiss 3T3 cells. FAK autophosphorylation was sensitive to inhibitors of p160/ROCK and coincided with the formation of stable complexes between FAK and Src family members.

UR - http://www.scopus.com/inward/record.url?scp=0034877755&partnerID=8YFLogxK

U2 - 10.1128/IAI.69.9.5931-5935.2001

DO - 10.1128/IAI.69.9.5931-5935.2001

M3 - Article

VL - 69

SP - 5931

EP - 5935

JO - Infection and Immunity

JF - Infection and Immunity

IS - 9

ER -