Estimation of Cortical Bone Strength Using CNN-based Regression Model

Hossam H. Sultan, Enrico Grisan, Laura Peralta, Sevan Harput

Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

5 Citations (Scopus)

Abstract

Cortical bone is a compact layer that acts as a protective surface and forms an external layer of all bones. With osteoporosis, imbalance between bone formation and bone loss occurs, and this leads to a deterioration of bone microstructure including cortical bone thinning. Therefore, there is a clinical need to estimate and assess bone strength and quality. The detection of bone cortical thickness is still challenging due to the high variance in the speed of sound in the cortical bone. The main aim of this study is to develop an accurate ultrasound method to estimate cortical bone thickness that could be used as a proxy of bone quality by using CNN-based regression models. To achieve this, pulse-echo measurements are performed at multiple ultrasound frequencies and the continuous wavelet transformations (CWT) of the acquired data was used as an input to the CNN. The maximum observed percentages were in 1 mm and 2 mm with an average error of 5.57%, and the minimum error was in group 7 (7mm) with a percentage of 1.6%. The preliminary results showed that combination of multi-frequency RF signals has potential to be used for cortical thickness estimation.

Original languageEnglish
Title of host publicationIUS 2022 - IEEE International Ultrasonics Symposium
PublisherIEEE Computer Society Press
ISBN (Electronic)9781665466578
DOIs
Publication statusPublished - 2022
Event2022 IEEE International Ultrasonics Symposium, IUS 2022 - Venice, Italy
Duration: 10 Oct 202213 Oct 2022

Publication series

NameIEEE International Ultrasonics Symposium, IUS
Volume2022-October
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2022 IEEE International Ultrasonics Symposium, IUS 2022
Country/TerritoryItaly
CityVenice
Period10/10/202213/10/2022

Keywords

  • Bone characterization
  • Chirp signal
  • Continuous wavelet transformation
  • Deep learning
  • Regression models

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