Ethyl glucuronide

Natalie E. Walsham, Roy Sherwood

    Research output: Contribution to journalLiterature reviewpeer-review

    63 Citations (Scopus)

    Abstract

    Alcohol is associated with significant morbidity and mortality. Subjects abusing alcohol can be identified through clinical history, examination or self-report questionnaires. A range of biomarkers is available for detecting alcohol misuse, but there is still a need for a marker that can detect alcohol consumption in the time window between one day (ethanol) and one week (gamma-glutamyl transpeptidase and carbohydrate-deficient transferrin). Ethyl glucuronide is a direct metabolite that can be detected in urine for up to 90 h and has the potential to become a useful marker of 'binge' drinking. As a non-invasive marker, it could have a role in a variety of clinical and forensic settings.

    Original languageEnglish
    Pages (from-to)110-117
    Number of pages8
    JournalAnnals of Clinical Biochemistry
    Volume49
    Issue number2
    DOIs
    Publication statusPublished - Mar 2012

    Keywords

    • RECENT ALCOHOL-CONSUMPTION
    • TANDEM MASS-SPECTROMETRY
    • DIRECT ETHANOL METABOLITES
    • LIQUID-CHROMATOGRAPHY
    • ORAL FLUID
    • HUMAN SERUM
    • LIVER-TRANSPLANTATION
    • RECENT DRINKING
    • EMERGENCY-ROOM
    • HEAVY DRINKERS

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